Professor
Christian Medical College Vellore, Ida Scudder Road, Vellore – 632004, Tamil Nadu, India
Mathew BS, Pulimood AB, Prasanna CG, Ramakrishna BS, Chandy SJ. Clofazimine induced enteropathy--a case highlighting the importance of drug induced disease in differential diagnosis. Trop Gastroenterol. 2006 Apr-Jun;27(2):87-8. PMID: 17089619.
Rajkumar P, Mathew BS, Das S, Isaiah R, John S, Prabha R, Fleming DH. Cisplatin Concentrations in Long and Short Duration Infusion: Implications for the Optimal Time of Radiation Delivery. J Clin Diagn Res. 2016 Jul;10(7):XC01-XC04. doi: 10.7860/JCDR/2016/18181.8126. Epub 2016 Jul 1. PMID: 27630935; PMCID: PMC5020194. Link
Aruldhas BW, Hoglund RM, Ranjalkar J, Tarning J, Mathew SK, Verghese VP, Bose A, Mathew BS. Optimization of dosing regimens of isoniazid and rifampicin in children with tuberculosis in India. Br J Clin Pharmacol. 2019 Mar;85(3):644-654. doi: 10.1111/bcp.13846. Epub 2019 Jan 17. PMID: 30588647; PMCID: PMC6379231. Link
Ranjalkar J, Mathew SK, Verghese VP, Bose A, Rose W, Gupta D, Fleming DH, Mathew BS. Isoniazid and rifampicin concentrations in children with tuberculosis with either a daily or intermittent regimen: implications for the revised RNTCP 2012 doses in India. Int J Antimicrob Agents. 2018 May;51(5):663-669. doi: 10.1016/j.ijantimicag.2017.12.004. Epub 2017 Dec 11. PMID: 29241821. Link
Samuel S, Mathew BS, Veeraraghavan B, Fleming DH, Chittaranjan SB, Prakash JA. In vitro study of elution kinetics and bio-activity of meropenem-loaded acrylic bone cement. J Orthop Traumatol. 2012 Sep;13(3):131-6. doi: 10.1007/s10195-012-0191-1. Epub 2012 Mar 30. PMID: 22461001; PMCID: PMC3427696.
S. Manvizhi, B.S. Mathew, Anil K. Kuruvilla, Kalpana Margaret Ernest, Saravana Kumar, V Balaji, Vigil James, Denise Fleming. Adequacy of the current recommended dosage of ciprofloxacin in preterm and term neonates with sepsis. Journal of Drug Delivery and Therapeutics. 2017; 7(3):102-105
Mathew BS, Pulimood AB, Prasanna CG, Ramakrishna BS, Chandy SJ. Clofazimine induced enteropathy--a case highlighting the importance of drug induced disease in differential diagnosis. Trop Gastroenterol. 2006 Apr-Jun;27(2):87-8. PMID: 17089619.
Rajkumar P, Mathew BS, Das S, Isaiah R, John S, Prabha R, Fleming DH. Cisplatin Concentrations in Long and Short Duration Infusion: Implications for the Optimal Time of Radiation Delivery. J Clin Diagn Res. 2016 Jul;10(7):XC01-XC04. doi: 10.7860/JCDR/2016/18181.8126. Epub 2016 Jul 1. PMID: 27630935; PMCID: PMC5020194. Link
Aruldhas BW, Hoglund RM, Ranjalkar J, Tarning J, Mathew SK, Verghese VP, Bose A, Mathew BS. Optimization of dosing regimens of isoniazid and rifampicin in children with tuberculosis in India. Br J Clin Pharmacol. 2019 Mar;85(3):644-654. doi: 10.1111/bcp.13846. Epub 2019 Jan 17. PMID: 30588647; PMCID: PMC6379231. Link
Ranjalkar J, Mathew SK, Verghese VP, Bose A, Rose W, Gupta D, Fleming DH, Mathew BS. Isoniazid and rifampicin concentrations in children with tuberculosis with either a daily or intermittent regimen: implications for the revised RNTCP 2012 doses in India. Int J Antimicrob Agents. 2018 May;51(5):663-669. doi: 10.1016/j.ijantimicag.2017.12.004. Epub 2017 Dec 11. PMID: 29241821. Link
Samuel S, Mathew BS, Veeraraghavan B, Fleming DH, Chittaranjan SB, Prakash JA. In vitro study of elution kinetics and bio-activity of meropenem-loaded acrylic bone cement. J Orthop Traumatol. 2012 Sep;13(3):131-6. doi: 10.1007/s10195-012-0191-1. Epub 2012 Mar 30. PMID: 22461001; PMCID: PMC3427696.
S. Manvizhi, B.S. Mathew, Anil K. Kuruvilla, Kalpana Margaret Ernest, Saravana Kumar, V Balaji, Vigil James, Denise Fleming. Adequacy of the current recommended dosage of ciprofloxacin in preterm and term neonates with sepsis. Journal of Drug Delivery and Therapeutics. 2017; 7(3):102-105
Miraclin TA, Mathew BS, Mammen JJ, Ramachandran SV, Kumar S, Bhattacharjee S, Sudarsanam TD, Sathyendra S, Prabhakar Abhilash KP, Jayaseelan V, Rupali P. Slow parasite clearance, absent K13-propeller gene polymorphisms and adequate artesunate levels among patients with malaria: A pilot study from southern India. Natl Med J India. 2019 Jul-Aug;32(4):200-206. doi: 10.4103/0970-258X.291292. PMID: 32769239. Link
Ratna P, Mathew BS, Annapandian VM, Saravanakumar K, Basu G, Tamilarasi V, Fleming DH. Pharmacokinetic drug interaction of mycophenolate with co-amoxiclav in renal transplant patients. Transplantation. 2011 Mar 27;91(6):e36-8. doi: 10.1097/TP.0b013e31820a6a79. PMID: 21383599.
Mathew BS, Fleming DH, Thomas M, Prabha R, Saravanakumar K. An initial experience with therapeutic drug monitoring of levetiracetam as reported from a pediatric clinical setting in India. Neurol India. 2012 Mar-Apr;60(2):146-9. doi: 10.4103/0028-3886.96382. PMID: 22626693.
Mathew BS, Prabha R, Basu G, Rajkumar P, Tamilarasi V, Fleming DH. Therapeutic drug monitoring of modified release once daily tacrolimus in de novo renal transplant with conversion to a twice daily generic in the stable period. J Pharmacol Pharmacother. 2015 Jul-Sep;6(3):156-9. doi: 10.4103/0976-500X.162019. PMID: 26312000; PMCID: PMC4544138.
Prabha R, Mathew BS, Jeyaseelan V, Kumar TS, Agarwal I, Fleming DH. Development and validation of limited sampling strategy equation for mycophenolate mofetil in children with systemic lupus erythematosus. Indian J Nephrol. 2016 Nov-Dec;26(6):408-412. doi: 10.4103/0971-4065.174242. PMID: 27942171; PMCID: PMC5131378.
Abiramalatha T, Mathew SK, Mathew BS, Shabeer MP, Arulappan G, Kumar M, Jayaseelan V, Kuruvilla KA. Continuous infusion versus intermittent bolus doses of fentanyl for analgesia and sedation in neonates: an open-label randomised controlled trial. Arch Dis Child Fetal Neonatal Ed. 2019 Jul;104(4):F433-F439. doi: 10.1136/archdischild-2018-315345. Epub 2018 Oct 15. PMID: 30322973. Link
Brunet M, van Gelder T, Åsberg A, Haufroid V, Hesselink DA, Langman L, Lemaitre F, Marquet P, Seger C, Shipkova M, Vinks A, Wallemacq P, Wieland E, Woillard JB, Barten MJ, Budde K, Colom H, Dieterlen MT, Elens L, Johnson-Davis KL, Kunicki PK, MacPhee I, Masuda S, Mathew BS, Millán O, Mizuno T, Moes DAR, Monchaud C, Noceti O, Pawinski T, Picard N, van Schaik R, Sommerer C, Vethe NT, de Winter B, Christians U, Bergan S. Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report. Ther Drug Monit. 2019 Jun;41(3):261-307. doi: 10.1097/FTD.0000000000000640. PMID: 31045868.
Abiramalatha T, Mathew SK, Mathew BS, Shabeer MP, Arulappan G, Kumar M, Jayaseelan V, Kuruvilla KA. Continuous infusion versus intermittent bolus doses of fentanyl for analgesia and sedation in neonates: an open-label randomised controlled trial. Arch Dis Child Fetal Neonatal Ed. 2019 Jul;104(4):F433-F439. doi: 10.1136/archdischild-2018-315345. Epub 2018 Oct 15. PMID: 30322973.
Das S, Fleming DH, Mathew BS, Winston A B, Prabhakar AT, Alexander M. Determination of serum carbamazepine concentration using dried blood spot specimens for resource-limited settings. Hosp Pract (1995). 2017 Apr;45(2):46-50. doi: 10.1080/21548331.2017.1296318. Epub 2017 Feb 22. PMID: 28353375.
Abiramalatha T, Mathew SK, Mathew BS, Shabeer MP, Arulappan G, Kumar M, Jayaseelan V, Kuruvilla KA. Continuous infusion versus intermittent bolus doses of fentanyl for analgesia and sedation in neonates: an open-label randomised controlled trial. Arch Dis Child Fetal Neonatal Ed. 2019 Jul;104(4):F433-F439. doi: 10.1136/archdischild-2018-315345. Epub 2018 Oct 15. PMID: 30322973.
Aruldhas BW, Hoglund RM, Ranjalkar J, Tarning J, Mathew SK, Verghese VP, Bose A, Mathew BS. Optimization of dosing regimens of isoniazid and rifampicin in children with tuberculosis in India. Br J Clin Pharmacol. 2019 Mar;85(3):644-654. doi: 10.1111/bcp.13846. Epub 2019 Jan 17. PMID: 30588647; PMCID: PMC6379231.
Mathew BS, Fleming DH, Prasanna S, Basu G, Chandy SJ, John GT. Mycophenolic acid estimation by pooled sampling: a novel strategy. Ther Drug Monit. 2010 Apr;32(2):141-4. doi: 10.1097/FTD.0b013e3181d3d051. PMID: 20216116.
Mathew BS, Fleming DH, Jeyaseelan V, Chandy SJ, Annapandian VM, Subbanna PK, John GT. A limited sampling strategy for tacrolimus in renal transplant patients. Br J Clin Pharmacol. 2008 Oct;66(4):467-72. doi: 10.1111/j.1365-2125.2008.03251.x. Epub 2008 Jun 28. PMID: 18662286; PMCID: PMC2561121.
Gopalakrishnan AV, Sunish SC, Mathew BS, Prabha R, Mathew SK. Stability of Vancomycin in Whole Blood. Ther Drug Monit. 2021 Jun 1;43(3):443-444. doi: 10.1097/FTD.0000000000000865. PMID: 33973967. Link
George SE, Singh G, Mathew BS, Fleming D, Korula G. Comparison of the effect of lignocaine instilled through the endotracheal tube and intravenous lignocaine on the extubation response in patients undergoing craniotomy with skull pins: A randomized double blind clinical trial. J Anaesthesiol Clin Pharmacol. 2013 Apr;29(2):168-72. doi: 10.4103/0970-9185.111668. PMID: 23878435; PMCID: PMC3713661.
Jahan A, Prabha R, Chaturvedi S, Mathew B, Fleming D, Agarwal I. Clinical efficacy and pharmacokinetics of tacrolimus in children with steroid-resistant nephrotic syndrome. Pediatr Nephrol. 2015 Nov;30(11):1961-7. doi: 10.1007/s00467-015-3133-3. Epub 2015 Jul 2. PMID: 26135137.
Naik GS, Kodagali R, Mathew BS, Thomas M, Prabha R, Mathew V, Fleming DH. Therapeutic Drug Monitoring of Levetiracetam and Lamotrigine: Is There a Need? Ther Drug Monit. 2015 Aug;37(4):437-44. doi: 10.1097/FTD.0000000000000158. PMID: 25478905.
Annapandian VM, John GT, Mathew BS, Fleming DH. Pharmacokinetic interaction between sodium valproate and mycophenolate in renal allograft recipients. Transplantation. 2009 Nov 15;88(9):1143-5. doi: 10.1097/TP.0b013e3181bb99ff. PMID: 19898213.
Mathew BS, John GT, Chandy SJ, Fleming DH. Stability issues of mycophenolic Acid in plasma: from patient to laboratory. ndian J Pharm Sci. 2009 Sep;71(5):559-61. doi: 10.4103/0250-474X.58193. PMID: 20502578; PMCID: PMC2866351.
Jacob J, Mathew SK, Chacko RT, Aruldhas BW, Singh A, Prabha R, Mathew BS. Systemic exposure to 5-fluorouracil and its metabolite, 5,6-dihydrofluorouracil, and development of a limited sampling strategy for therapeutic drug management of 5-fluorouracil in patients with gastrointestinal malignancy. Br J Clin Pharmacol. 2021 Mar;87(3):937-945. doi: 10.1111/bcp.14444. Epub 2020 Jul 26. PMID: 32592630.
Mathew, Sumith & A, Blessed & Mathew, Aswathy & Jacob, Jeana & Prabha, Ratna & Mathew, Binu. (2019). Development and validation of indocyanine green assay in human plasma using High-Performance Liquid Chromatography with PDA detector. International Journal of Research in Pharmaceutical Sciences. 10. 1007-1012. 10.26452/ijrps.v10i2.373.
Prabha R, Mathew SK, Joseph A J, Mathew BS. Determination of thiopurine S-methyltransferase activity using reverse-phase high-performance liquid chromatography assay with ultraviolet detection: Reference values for the Indian population. J Pharmacol Pharmacother 2019;10:105-10 Link
Mathew SK, Mathew BS, Neely MN, Naik GS, Prabha R, Jacob GG, K S, Fleming DH. A Nonparametric Pharmacokinetic Approach to Determine the Optimal Dosing Regimen for 30-Minute and 3-Hour Meropenem Infusions in Critically Ill Patients. Ther Drug Monit. 2016 Oct;38(5):593-9. doi: 10.1097/FTD.0000000000000323. PMID: 27454665. Link
Jahan A, Prabha R, Chaturvedi S, Mathew B, Fleming D, Agarwal I. Clinical efficacy and pharmacokinetics of tacrolimus in children with steroid-resistant nephrotic syndrome. Pediatr Nephrol. 2015 Nov;30(11):1961-7. doi: 10.1007/s00467-015-3133-3. Epub 2015 Jul 2. PMID: 26135137.
George SE, Singh G, Mathew BS, Fleming D, Korula G. Comparison of the effect of lignocaine instilled through the endotracheal tube and intravenous lignocaine on the extubation response in patients undergoing craniotomy with skull pins: A randomized double blind clinical trial. J Anaesthesiol Clin Pharmacol. 2013 Apr;29(2):168-72. doi: 10.4103/0970-9185.111668. PMID: 23878435; PMCID: PMC3713661. Link
Manvizhi S, Mathew BS, Fleming DH, Basu G, John GT. Combined approach with therapeutic drug monitoring and pharmacogenomics in renal transplant recipients. Indian J Nephrol. 2013 Jan;23(1):71-3. doi: 10.4103/0971-4065.107216. PMID: 23580812; PMCID: PMC3621246. Link
Manvizhi S, Mathew BS, Fleming DH, Basu G, John GT. Combined approach with therapeutic drug monitoring and pharmacogenomics in renal transplant recipients. Indian J Nephrol. 2013 Jan;23(1):71-3. doi: 10.4103/0971-4065.107216. PMID: 23580812; PMCID: PMC3621246. Link
Fleming DH, Mathew BS, Prasanna S, Annapandian VM, John GT. A possible simplification for the estimation of area under the curve (AUC₀₋₁₂) of enteric-coated mycophenolate sodium in renal transplant patients receiving tacrolimus. Ther Drug Monit. 2011 Apr;33(2):165-70. doi: 10.1097/FTD.0b013e31820c16f8. PMID: 21383656.
Annapandian VM, Fleming DH, Mathew BS, John GT. Mycophenolic acid area under the curve recovery time following rifampicin withdrawal. Indian J Nephrol. 2010 Jan;20(1):51-3. doi: 10.4103/0971-4065.62091. PMID: 20535273; PMCID: PMC2878413.
Mathew BS, Fleming DH, Gupta M, Kumar R, Kumar D, Chandy SJ, Balraj V. An objective measure of antibiotic use for febrile illness in a rural paediatric population using high performance liquid chromatography. Indian J Med Res. 2010 May;131:723-5. PMID: 20516547. Link
Mathew BS, Mathew SK, Aruldhas BW, Prabha R, Gangadharan N, David VG, Varughese S, John GT. Analytical and clinical validation of dried blood spot and volumetric absorptive microsampling for measurement of tacrolimus and creatinine after renal transplantation. Clin Biochem. 2022 Jul-Aug;105-106:25-34. doi: 10.1016/j.clinbiochem.2022.04.014. Epub 2022 Apr 28. PMID: 35490728. Link
Mathew SK, Rao SV, Prabha R, Neely MN, Mathew BS, Aruldhas BW, Veeraraghavan B, Kandasamy S. Model-Informed Rationale for Early Therapeutic Drug Monitoring of Colistin in Critically Ill Patients. J Clin Pharmacol. 2023 Jan;63(1):57-65. doi: 10.1002/jcph.2130. Epub 2022 Aug 24. PMID: 35924629.
Alexander S, Fleming DH, Mathew BS, Varughese S, Jeyaseelan V, Tamilarasi V, Jacob CK, John GT. Pharmacokinetics of concentration-controlled mycophenolate mofetil in proliferative lupus nephritis: an observational cohort study. Ther Drug Monit. 2014 Aug;36(4):423-32. doi: 10.1097/FTD.0000000000000031. PMID: 25014074.
Manesh A, Devasagayam E, Bhanuprasad K, Mathew SK, Karthik R, Mathew BS, Varghese GM. Efficacy of Crushed Delayed-Release Posaconazole Tablets in Rhino-Orbito-Cerebral Mucormycosis. Antimicrob Agents Chemother. 2022 Dec 20;66(12):e0108522. doi: 10.1128/aac.01085-22. Epub 2022 Nov 15. PMID: 36377934; PMCID: PMC9765161.
Mathew BS, Fleming DH, Annapandian VM, Prasanna S, Prasanna CG, Chandy SJ, John GT. A reliable limited sampling strategy for the estimation of mycophenolic acid area under the concentration time curve in adult renal transplant patients in the stable posttransplant period. Ther Drug Monit. 2010 Apr;32(2):136-40. doi: 10.1097/FTD.0b013e3181cd550f. PMID: 20110849. Link
Prasanna Kumar T. Subbanna Sujith J Chandy, Debashish Danda, Binu S Mathew Research Letter - Correlation between serum methotrexate concentrations and disease remission status in rheumatoid arthritis patients on triple disease-modifying antirheumatic drug therapy Indian Journal of Pharmacology March 2007:39(2) : 117-8 DOI: 10.4103/0253-7613.32532 SourceOAI Prasanna Kumar T. SubbannaSujith J ChandySujith J ChandyDebashish DandaDebashish DandaBinu S MathewBinu S Mathew
Subbanna PK, Margaret Shanti FX, George J, Tharion G, Neelakantan N, Durai S, Chandy SJ, Mathew BS, Suresh R. Topical phenytoin solution for treating pressure ulcers: a prospective, randomized, double-blind clinical trial. Spinal Cord. 2007 Nov;45(11):739-43. doi: 10.1038/sj.sc.3102029. Epub 2007 Feb 6. PMID: 17279096.
Fleming DH, Mathew BS, John GT, Chandy SJ, Manivannan J, Jeyaseelan V. A six-hour extrapolated sampling strategy for monitoring mycophenolic acid in renal transplant patients in the Indian subcontinent. J Postgrad Med. 2006 Oct-Dec;52(4):248-52. PMID: 17102540. Link
Mathew BS, Pulimood AB, Prasanna CG, Ramakrishna BS, Chandy SJ. Clofazimine induced enteropathy--a case highlighting the importance of drug induced disease in differential diagnosis. Trop Gastroenterol. 2006 Apr-Jun;27(2):87-8. PMID: 17089619. Link
Indian Journal of Medical ethics
Manesh A, Devasagayam E, Bhanuprasad K, Varghese L, Kurien R, Cherian LM, Dayanand D, George MM, Kumar SS, Karthik R, Vanjare H, Peter J, Michael JS, Thomas M, Mathew BS, Samuel P, Peerawaranun P, Mukaka M, Rupa V, Varghese GM. Short intravenous amphotericin B followed by oral posaconazole using a simple, stratified treatment approach for diabetes or COVID-19-associated rhino-orbito-cerebral mucormycosis: a prospective cohort study. Clin Microbiol Infect. 2023 Oct;29(10):1298-1305. doi: 10.1016/j.cmi.2023.06.017. Epub 2023 Jun 20. PMID: 37348653; PMCID: PMC10281032.
Wilfred PM, Mathew S, Chacko B, Prabha R, Mathew BS. Estimation of Free Phenytoin Concentration in Critically Ill Patients with Hypoalbuminemia: Direct-measurement vs Traditional Equations. Indian J Crit Care Med 2022; 26 (6):682-687. DOI: 10.5005/jp-journals-10071-24235
Gafar F, Wasmann RE, McIlleron HM, Aarnoutse RE, Schaaf HS, Marais BJ, Agarwal D, Antwi S, Bang ND, Bekker A, Bell DJ, Chabala C, Choo L, Davies GR, Day JN, Dayal R, Denti P, Donald PR, Engidawork E, Garcia-Prats AJ, Gibb D, Graham SM, Hesseling AC, Heysell SK, Idris MI, Kabra SK, Kinikar A, Kumar AKH, Kwara A, Lodha R, Magis-Escurra C, Martinez N, Mathew BS, Mave V, Mduma E, Mlotha-Mitole R, Mpagama SG, Mukherjee A, Nataprawira HM, Peloquin CA, Pouplin T, Ramachandran G, Ranjalkar J, Roy V, Ruslami R, Shah I, Singh Y, Sturkenboom MGG, Svensson EM, Swaminathan S, Thatte U, Thee S, Thomas TA, Tikiso T, Touw DJ, Turkova A, Velpandian T, Verhagen LM, Winckler JL, Yang H, Yunivita V, Taxis K, Stevens J, Alffenaar JC; Global Collaborative Group for Meta-Analysis of Paediatric Individual Patient Data in Pharmacokinetics of Anti-TB Drugs. Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis. Eur Respir J. 2023 Mar 9;61(3):2201596. doi: 10.1183/13993003.01596-2022. PMID: 36328357; PMCID: PMC9996834.
Mathew SK, Rao SV, Prabha R, Neely MN, Mathew BS, Aruldhas BW, Veeraraghavan B, Kandasamy S. Model-Informed Rationale for Early Therapeutic Drug Monitoring of Colistin in Critically Ill Patients. J Clin Pharmacol. 2023 Jan;63(1):57-65. Link
Sivamani P, Eriyat V, Mathew SK, Singh A, Aaron R, Chacko RT, Joel A, Prabha R, Mathew BS. Identification of DPYD variants and estimation of uracil and dihydrouracil in a healthy Indian population. Per Med. 2023 Jan;20(1):39-53. doi: 10.2217/pme-2022-0042. Epub 2022 Nov 23. PMID: 36416570.
Mathew, Sumith K et al. “Genetic predisposition and high exposure to colistin in the early treatment period as independent risk factors for colistin-induced nephrotoxicity.” Clinical and translational science vol. 17,3 (2024): e13764. doi:10.1111/cts.13764