The IRB has approved and funded a study on Antimullerian hormone levels in normal ovulatory women. Positive findings from this study will help in the assisted reproductive technology offered in our hospital. – Mrs.S.Vanitha and Dr.Victoria Job.
The department is collaborating with the Endocrinology Department in a clamp study called ‘The impact of Vitamin D replacement on indices on insulin sensitivity and resistance in subjects with Vitamin D deficiency’ – Dr.Joe Fleming and Dr.F.S.Geethanjali.
There is a wide spectrum of Organophosphorous metabolism observed in OP self poisoned patients. Differences in OP handling by patients are due to the level and chemical nature of the ingested OP compound, and differences in metabolism and clearance of OP compounds in the body. This is due to inter individual variations in many enzymes including, red blood cell acetyl cholinesterase, serum cholinesterase, serum paraoxonase, serum arylesterase. We are interested in identifying and characterizing OP compound ingested in patients ,PON1status, and other enzymes involved in the metabolism of OP. Correlate with clinical outcome to understand this heterogeneity – Dr.R.Selvakumar, Dr.Joe Fleming and Mr.Arun Jose.
INCLAP Project – This project initiated by ICMR to establish reference interval for the Indian population. This is an ambitious project where in it envisages to collect more than half million blood samples from all parts of India and establish the reference interval for more than 250 parameters. Dr.R.Selvakumar is involved in this project as an expert and incharge of the quality control for the project.
The department along with obstetric and gynecology is also involved in a study to evaluate serum markers that aid in the diagnosis of preclampisa – soluble fms like tyrosine kinase I and placental growth factor – Dr.Victoria Job.
