Winston AB, Vazhudhi K, Sen S, Thomas E, Benjamin S, Peedicayil J. Inhibition by sildenafil of contractility of isolated non-pregnant human myometrium. J Pharmacol Pharmacother. 2015 Jul-Sep;6(3):136-41. doi: 10.4103/0976-500X.162020. PMID: 26311996; PMCID: PMC4544134.

Peedicayil J. Exposure to Enriched Environment May Act Epigenetically to Correct Defects due to Chronic Restraint Stress in Rats. Int J Appl Basic Med Res. 2019 Apr-Jun;9(2):124-125. doi: 10.4103/ijabmr.IJABMR_389_18. PMID: 31041179; PMCID: PMC6477953.

Peedicayil, J. and Kumar, A. Epigenetic Drugs for Mood Disorders Prog Mol Biol Transl Sci; 2018, 157 151-174 Link

Naik GS, Kodagali R, Tyagi MG, Ernest K, Shanthi M, Mathew SK, Peedicayil J. Inhibition of Spontaneous Contractility of Isolated Caprine Ureter by Flupirtine. Int J Appl Basic Med Res. 2018 Apr-Jun;8(2):116-119. doi: 10.4103/ijabmr.IJABMR_159_17. PMID: 29744325; PMCID: PMC5932919.

Peedicayil, J. An epigenetic role for ascorbic acid in neurodegenerative diseases Cns Neuroscience & Therapeutics; 2018, 24 (9): 841-841 Link

Peedicayil J, Grayson DR. Some implications of an epigenetic-based omnigenic model of psychiatric disorders. J Theor Biol. 2018 Sep 7;452:81-84. doi: 10.1016/j.jtbi.2018.05.014. Epub 2018 May 22. PMID: 29775682; PMCID: PMC6544390.

Winston AB, Vazhudhi K, Sen S, Thomas E, Benjamin S, Peedicayil J. Inhibition by sildenafil of contractility of isolated non-pregnant human myometrium. J Pharmacol Pharmacother. 2015 Jul-Sep;6(3):136-41. doi: 10.4103/0976-500X.162020. PMID: 26311996; PMCID: PMC4544134.

Peedicayil J. Exposure to Enriched Environment May Act Epigenetically to Correct Defects due to Chronic Restraint Stress in Rats. Int J Appl Basic Med Res. 2019 Apr-Jun;9(2):124-125. doi: 10.4103/ijabmr.IJABMR_389_18. PMID: 31041179; PMCID: PMC6477953.

Peedicayil, J. and Kumar, A. Epigenetic Drugs for Mood Disorders Prog Mol Biol Transl Sci; 2018, 157 151-174 Link

Naik GS, Kodagali R, Tyagi MG, Ernest K, Shanthi M, Mathew SK, Peedicayil J. Inhibition of Spontaneous Contractility of Isolated Caprine Ureter by Flupirtine. Int J Appl Basic Med Res. 2018 Apr-Jun;8(2):116-119. doi: 10.4103/ijabmr.IJABMR_159_17. PMID: 29744325; PMCID: PMC5932919.

Peedicayil, J. An epigenetic role for ascorbic acid in neurodegenerative diseases Cns Neuroscience & Therapeutics; 2018, 24 (9): 841-841 Link

Peedicayil J, Grayson DR. Some implications of an epigenetic-based omnigenic model of psychiatric disorders. J Theor Biol. 2018 Sep 7;452:81-84. doi: 10.1016/j.jtbi.2018.05.014. Epub 2018 May 22. PMID: 29775682; PMCID: PMC6544390.

Peedicayil J, Grayson DR. An epigenetic basis for an omnigenic model of psychiatric disorders. J Theor Biol. 2018 Apr 14;443:52-55. doi: 10.1016/j.jtbi.2018.01.027. Epub 2018 Jan 31. PMID: 29378208; PMCID: PMC6512988.

Sen S, Thomas A, Das S, Dey JK, Peedicayil A, Thomas V, Peedicayil J. Inhibition by tadalafil of contractility of isolated nonpregnant human myometrium. J Pharmacol Pharmacother. 2016 Oct-Dec;7(4):177-181. doi: 10.4103/0976-500X.195902. PMID: 28163539; PMCID: PMC5242031.

Peedicayil J. L-Acetylcarnitine as a histone acetylation modulator in psychiatric disorders. Psychopharmacology (Berl). 2018 Nov;235(11):3361-3362. doi: 10.1007/s00213-018-5043-0. Epub 2018 Sep 24. PMID: 30251161.

Peedicayil J. Epigenetics as a link between psychosocial factors and mental disorders. Indian journal of psychiatry, 57(2), 218. doi.org/10.4103/0019-5545.158208

Peedicayil J. Epigenetic approaches for bipolar disorder drug discovery. Expert Opin Drug Discov. 2014 Aug;9(8):917-30. doi: 10.1517/17460441.2014.922537. Epub 2014 May 29. PMID: 24875048.

J Peedicayil Epigenetics and the war on mental illness Molecular Psychiatry 2014: 19: 960 doi:10.1038/mp.2014.16

Peedicayil J. Epigenetic drugs in cognitive disorders. Curr Pharm Des. 2014;20(11):1840-6. doi: 10.2174/13816128113199990526. PMID: 23888959.

Jacob Peedicayil Epigenetic Drugs for Alzheimer's Disease British Journal of Clinical Pharmacology 2012: 75(4): 1152-53 10.1111/j.1365-2125.2012.04444.x

Jacob Peedicayil The Role of Epigenetics in Altered Gene Expression Involved in GABAergic Transmission in the Cerebellum of Schizophrenia Patients May 2009American Journal of Psychiatry 166(4):493-4 DOI: 10.1176/appi.ajp.2009.09010011

Faruqui AR, Mathai J, George J, Peedicayil J, Ernest K, Neelakantan N. Inhibitory effect of nicorandil on the contraction of isolated human urinary bladder detrusor muscle. Methods Find Exp Clin Pharmacol. 2008 Jun;30(5):363-6. doi: 10.1358/mf.2008.30.5.1186078. PMID: 18806895.

JACOB PEEDICAYIL Genes underlying common complex diseases, International Journal of Epidemiology, Volume 35, Issue 2, April 2006, Pages 490–491 doi.org/10.1093/ije/dyi297

Peedicayil J. Epigenetic therapy--a new development in pharmacology. Indian J Med Res. 2006 Jan;123(1):17-24. PMID: 16567863 Link

Peedicayil J. Epialleles and common disease. Med Hypotheses. 2005;64(1):215. doi: 10.1016/j.mehy.2004.09.003. PMID: 15533644. Link

Peedicayil J. The relevance of epigenomics to psychiatry. Am J Psychiatry. 2004 Aug;161(8):1502-3. doi: 10.1176/appi.ajp.161.8.1502-a. PMID: 15285990. Link

Peedicayil J. Future strategies in psychiatric genetics. Med Hypotheses. 2003 Feb;60(2):215-7. doi: 10.1016/s0306-9877(02)00361-4. PMID: 12606238.

Peedicayil J, Deendayal M, Sadasivan G, Shivaji S. Assessment of hyperactivation, acrosome reaction and motility characteristics of spermatozoa from semen of men of proven fertility and unexplained infertility. Andrologia. 1997 Jul-Aug;29(4):209-18. doi: 10.1111/j.1439-0272.1997.tb00318.x. PMID: 9263571. Link

Naik GS, Kodagali R, Tyagi MG, Ernest K, Shanthi M, Mathew SK, Peedicayil J. Inhibition of Spontaneous Contractility of Isolated Caprine Ureter by Flupirtine. Int J Appl Basic Med Res. 2018 Apr-Jun;8(2):116-119. doi: 10.4103/ijabmr.IJABMR_159_17. PMID: 29744325; PMCID: PMC5932919. Link

Mathew SK, Naik GS, Peedicayil J. Inhibition by Benidipine of Contractility of Isolated Proximal and Distal Caprine Ureter. Int J Appl Basic Med Res. 2017 Jul-Sep;7(3):155-159. doi: 10.4103/ijabmr.IJABMR_87_16. PMID: 28904913; PMCID: PMC5590376.

Peedicayil J. The Role of Epigenetics in the Pathogenesis and Potential Treatment of Attention Deficit Hyperactivity Disorder. Curr Neuropharmacol. 2021 Sep 19. doi: 10.2174/1570159X19666210920091036. Epub ahead of print. PMID: 34544344.

Peedicayil J. The Potential Role of Epigenetic Drugs in the Treatment of Anxiety Disorders. Neuropsychiatr Dis Treat. 2020 Mar 2;16:597-606. doi: 10.2147/NDT.S242040. PMID: 32184601; PMCID: PMC7060022.

Peedicayil J. L-Acetylcarnitine as a histone acetylation modulator in psychiatric disorders. Psychopharmacology (Berl). 2018 Nov;235(11):3361-3362. doi: 10.1007/s00213-018-5043-0. Epub 2018 Sep 24. PMID: 30251161.

Peedicayil J. L-Acetylcarnitine as a histone acetylation modulator in psychiatric disorders. Psychopharmacology (Berl). 2018 Nov;235(11):3361-3362. doi: 10.1007/s00213-018-5043-0. Epub 2018 Sep 24. PMID: 30251161.

Peedicayil J. L-Acetylcarnitine as a histone acetylation modulator in psychiatric disorders. Psychopharmacology (Berl). 2018 Nov;235(11):3361-3362. doi: 10.1007/s00213-018-5043-0. Epub 2018 Sep 24. PMID: 30251161.

Peedicayil J. L-Acetylcarnitine as a histone acetylation modulator in psychiatric disorders. Psychopharmacology (Berl). 2018 Nov;235(11):3361-3362. doi: 10.1007/s00213-018-5043-0. Epub 2018 Sep 24. PMID: 30251161.

Peedicayil J. L-Acetylcarnitine as a histone acetylation modulator in psychiatric disorders. Psychopharmacology (Berl). 2018 Nov;235(11):3361-3362. doi: 10.1007/s00213-018-5043-0. Epub 2018 Sep 24. PMID: 30251161.

Peedicayil J. Preclinical epigenetic models for screening epigenetic drugs for schizophrenia. J Pharmacol Toxicol Methods. 2016 Jan-Feb;77:1-5. doi: 10.1016/j.vascn.2015.09.002. Epub 2015 Sep 11. PMID: 26370661.

Peedicayil J. Epigenetic Drugs for Multiple Sclerosis. Curr Neuropharmacol. 2016;14(1):3-9. doi: 10.2174/1570159x13666150211001600. PMID: 26813117; PMCID: PMC4787283. Link

Peedicayil J. A comparison of Erikson's Epigenetic Principle with epigenetics. J Theor Biol. 2012 Dec 21;315:144-5. doi: 10.1016/j.jtbi.2012.09.010. Epub 2012 Sep 18. PMID: 22999979.

Peedicayil J. Role of epigenetics in pharmacotherapy, psychotherapy and nutritional management of mental disorders. J Clin Pharm Ther. 2012 Oct;37(5):499-501. doi: 10.1111/j.1365-2710.2012.01346.x. Epub 2012 Mar 26. PMID: 22449320. Link

Peedicayil J. The role of DNA methylation in the pathogenesis and treatment of cancer. Curr Clin Pharmacol. 2012 Nov;7(4):333-40. doi: 10.2174/157488412803305858. PMID: 22794162. Link

Peedicayil J, Aniket Kumar Time for clinical trials of epigenetic drugs in psychiatric disorders? British Journal of Clinical Pharmacology 2011 :73 : 309-10 Link

Peedicayil, Jacob Epigenetic management of major psychosis.” Clinical epigenetics vol. 2,2 (2011): 249-56. doi:10.1007/s13148-011-0038-2

Jacob Peedicayil Epigenetic Basis of Individual Variability to Major Psychosis Current Pharmacogenomics and Personalized Medicine 2010: 8(3): 232-39 doi: 10.2174/187569210792246290

Prabhakaran SS, Dhanasekar KR, Thomas E, Jose R, Peedicayil J, Samuel P. Inhibition of isolated human myometrium contractility by minoxidil and reversal by glibenclamide. Methods Find Exp Clin Pharmacol. 2010 Mar;32(2):97-100. doi: 10.1358/mf.2010.32.2.1434163. PMID: 20401345.

George N, Shiny PJ, Miriam J, Nancy CA, Dhanasekar KR, Peedicayil J. Inhibitory effect of anticholinergics on the contraction of isolated caprine urinary bladder detrusor muscle. Auton Autacoid Pharmacol. 2010 Jul;30(3):173-7. doi: 10.1111/j.1474-8673.2009.00447.x. Epub 2010 Jan 19. PMID: 20085574.

Peedicayil J, Thangavelu P. Purkinje cell loss in autism may involve epigenetic changes in the gene encoding GAD. Med Hypotheses. 2008 Dec;71(6):978. doi: 10.1016/j.mehy.2008.07.038. Epub 2008 Sep 9. PMID: 18783896. Link

Peedicayil J. Beyond genomics: epigenetics and epigenomics. Clin Pharmacol Ther. 2008 Jul;84(1):25-6. doi: 10.1038/clpt.2008.26. Epub 2008 Feb 27. PMID: 18305453. Link

Jacob Peedicayil Abraham Psychosocial factors may act via epigenetic mechanisms in the pathogenesis of mental disorders Link

Peedicayil J. Epigenetic mechanisms may underlie the increased risk for psychosis among immigrants. Med Hypotheses. 2008;70(1):211. doi: 10.1016/j.mehy.2007.04.002. Epub 2007 May 23. PMID: 17512123.

Peedicayil, Jacob The role of epigenetics in mental disorders, Indian Journal of Medical Research: August 2007 - Volume 126 - Issue 2 - p 105-111 Link

Jacob Peedicayil, Prasanna Kumar T Subbanna Revisiting the methylation hypothesis for the psychoses Medical Hypotheses 2007: 68: 721 Link

Parimala K, Peedicayil J, Peedicayil A, Nelson N, Ernest K. The effect of a nicorandil congener on isolated human myometrium. Eur J Obstet Gynecol Reprod Biol. 2006 Jun 1;126(2):176-9. doi: 10.1016/j.ejogrb.2005.08.014. Epub 2005 Oct 10. PMID: 16216408.

Peedicayil J. DNA methylation and the central dogma of molecular biology. Med Hypotheses. 2005;64(6):1243-4. doi: 10.1016/j.mehy.2004.12.022. PMID: 15823731. Link

Peedicayil J. Psychosocial factors in the pathogenesis of mental disorders. Br J Psychiatry. 2004 Dec;185:520. doi: 10.1192/bjp.185.6.520-a. PMID: 15572746. Link

Peedicayil J. The importance of cultural inheritance. Med Hypotheses. 2001 Feb;56(2):158-9. doi: 10.1054/mehy.2000.1131. PMID: 11425279.

Mathew SK, Naik GS, Peedicayil J. Inhibition by Benidipine of Contractility of Isolated Proximal and Distal Caprine Ureter. Int J Appl Basic Med Res. 2017 Jul-Sep;7(3):155-159. doi: 10.4103/ijabmr.IJABMR_87_16. PMID: 28904913; PMCID: PMC5590376.

Peedicayil J. Folic acid and its congeners in the treatment of schizophrenia. Psychopharmacology (Berl). 2019 Apr;236(4):1401-1402. doi: 10.1007/s00213-018-5095-1. Epub 2018 Oct 31. PMID: 30382355.

Peedicayil J. Pharmacoepigenetics and Pharmacoepigenomics: An Overview. Curr Drug Discov Technol. 2019;16(4):392-399. doi: 10.2174/1570163815666180419154633. PMID: 29676232.

J Peedicayil The Epigenome in Personalized Medicine Clinical Pharmacology and Therapeutics 2013: 93: Pages: 149-150 doi: 10.1038/clpt.2012.182

Jacob Peedicayil, MD The Role of Epigenetics in the Raised Incidence Rates of Psychoses Among Migrant Groups Arch Gen Psychiatry. 2009;66(5):564. doi:10.1001/archgenpsychiatry.2009.28

Peedicayil J. Epigenetic biomarkers in psychiatric disorders. British journal of pharmacology, 155(6), 795–796 doi.org/10.1038/bjp.2008.254

Jacob Peedicayil The importance of cultural inheritance Medical Hypotheses 56(2):158-9 DOI: 10.1054/mehy.2000.1131

Kumar A, Prabha R, Paul T, Margaret Shanthi FX, George J, Peedicayil J, Ernest K. Tramadol inhibits the contractility of isolated caprine detrusor muscle. Auton Autacoid Pharmacol. 2012 Apr;32(1 Pt 2):15-22. doi: 10.1111/j.1474-8673.2012.00470.x. Epub 2012 Feb 29. PMID: 22372564.

Shah NH, Thomas E, Jose R, Peedicayil J. Tramadol inhibits the contractility of isolated human myometrium. Auton Autacoid Pharmacol. 2013 Apr;33(1-2):1-5. doi: 10.1111/aap.12003. Epub 2013 Feb 22. PMID: 23433451.

Peedicayil J. The relevance of polycomb group proteins to the development of psychiatric disorders. Front Cell Dev Biol. 2022 Jul 22;10:927833. doi: 10.3389/fcell.2022.927833. PMID: 35938156; PMCID: PMC9354779.

Peedicayil J. The role of epigenetics in social psychiatry. Int J Soc Psychiatry. 2017 Feb;63(1):14-20. doi: 10.1177/0020764016677556. Epub 2016 Nov 18. PMID: 27856950.

Joseph S, Maria SA, Peedicayil J. Drugs Currently Undergoing Preclinical or Clinical Trials for the Treatment of Overactive Bladder: A Review. Curr Ther Res Clin Exp. 2022 Apr 6;96:100669. doi: 10.1016/j.curtheres.2022.100669. PMID: 35494662; PMCID: PMC9052038.

Peedicayil J. Genome-Environment Interactions and Psychiatric Disorders. Biomedicines. 2023 Apr 19;11(4):1209. doi: 10.3390/biomedicines11041209. PMID: 37189827; PMCID: PMC10136093. Link

Dhruva A, Hamsavardhini VK, Kamatham S, Kataria A, Kumar A, Shanthi M, Peedicayil J. Avanafil Inhibits the Contractility of the Isolated Caprine Detrusor Muscle. Int J Appl Basic Med Res. 2019 Oct-Dec;9(4):231-235. doi: 10.4103/ijabmr.IJABMR_339_18. Epub 2019 Oct 11. PMID: 31681549; PMCID: PMC6822320.

Peedicayil J. L-Acetylcarnitine as a histone acetylation modulator in psychiatric disorders. Psychopharmacology (Berl). 2018 Nov;235(11):3361-3362. doi: 10.1007/s00213-018-5043-0. Epub 2018 Sep 24. PMID: 30251161.

Jacob Peedicayil Abraham The role of epigenetics in seasonal changes in mood disorders Psychopharmacology 2018:20: 668

Peedicayil J. The relevance of epigenetics to seasonal affective disorder. J Affect Disord. 2018 Oct 15;239:201-202. doi: 10.1016/j.jad.2018.07.015. Epub 2018 Jul 10. PMID: 30014960.

Peedicayil, Jacob. An epigenetic role for ascorbic acid in neurodegenerative diseases.” CNS neuroscience & therapeutics vol. 24,9 (2018): 841. doi:10.1111/cns.12982

Peedicayil J. Epigenetics and developmental psychiatry. Int J Soc Psychiatry. 2017 Jun;63(4):378. doi: 10.1177/0020764017693656. Epub 2017 Mar 7. PMID: 28504044.

Jacob Peedicayil Psychiatric Epigenetics: A Personal Perspective Journal of Clinical Epigenetics 2016: 2: 20 Link

Peedicayil J. Epigenetic targets for the treatment of neurodegenerative diseases. Clin Pharmacol Ther. 2016 May;99(5):481. doi: 10.1002/cpt.323. Epub 2016 Jan 12. PMID: 26669276.

Peedicayil J. Epigenetic targets for the treatment of neurodegenerative diseases. Clin Pharmacol Ther. 2016 May;99(5):481. doi: 10.1002/cpt.323. Epub 2016 Jan 12. PMID: 26669276.

Shah NH, Thomas E, Jose R, Peedicayil J. Tramadol inhibits the contractility of isolated human myometrium. Auton Autacoid Pharmacol. 2013 Apr;33(1-2):1-5. doi: 10.1111/aap.12003. Epub 2013 Feb 22. PMID: 23433451.

Jacob Peedicayil Pharmacoepigenetics and pharmacoepigenomics Pharmacogenomics Jan 2009 9(12):1785-6 DOI: 10.2217/14622416.9.12.1785 Jacob Peedicayil

Thomas M, Peedicayil J, Koshi T, Korah I. Adverse reactions to radiocontrast media in an Indian population. Br J Radiol. 1999 Jul;72(859):648-52. doi: 10.1259/bjr.72.859.10624321. PMID: 10624321. Link

Shivaji S, Peedicayil J, Girija Devi L. Analysis of the motility parameters of in vitro hyperactivated hamster spermatozoa. Mol Reprod Dev. 1995 Oct;42(2):233-47. doi: 10.1002/mrd.1080420213 PMID: 8562069.

Jacob Peedicayil Prolactin is synthesized and secreted by the endometrium Biological Psychiatry September 15, 1995: 38: 417p Link

Jacob Peedicayil A study on serum prolactin levels in schizophrenia: Correlation with positive and negative symptoms International Clinical Psychopharmacology 1993: 8: 177-179 Link

Kuruvilla A, Peedicayil J, Srikrishna G, Kuruvilla K, Kanagasabapathy AS. A study of serum prolactin levels in schizophrenia: comparison of males and females. Clin Exp Pharmacol Physiol. 1992 Sep;19(9):603-6. doi: 10.1111/j.1440-1681.1992.tb00511.x. PMID: 1356671.

Kuruvilla A, Srikrishna G, Peedicayil J, Kuruvilla K, Kanagasabapathy AS. Serum prolactin levels in manic patients. Biol Psychiatry. 1991 Aug 15;30(4):421-3. doi: 10.1016/0006-3223(91)90301-2. PMID: 1680474.

Peedicayil J, Ernest K, Thomas M, Kanagasabapathy AS, Stephen PM. The effect of organophosphorus compounds on serum pseudocholinesterase levels in a group of industrial workers. Hum Exp Toxicol. 1991 Jul;10(4):275-8. doi: 10.1177/096032719101000406. PMID: 1679650.

Peedicayil, J., Abraham, A., & Thomas, M. (1988). The effect of diazepam on memory in a group of patients with anxiety neurosis. Current Therapeutic Research, 44(3), 385–390. Link

Peedicayil J. Epigenetics as a link between psychosocial factors and mental disorders. Indian J Psychiatry. 2015 Apr-Jun;57(2):218. doi: 10.4103/0019-5545.158208. PMID: 26124535; PMCID: PMC4462798.

Peedicayil J, Aruldhas BW. The relevance of epigenetics and epigenomics to pharmacometrics. Epigenomics. 2023 May;15(9):539-541. doi: 10.2217/epi-2023-0177. Epub 2023 Jul 5. PMID: 37403947.

Maria SA, Kumar A, Wilfred PM, Shanthi M, Peedicayil J. Inhibition of Contractility of Isolated Caprine Detrusor by the Calcium Channel Blocker Cilnidipine and Reversal by Calcium Channel Openers. Curr Ther Res Clin Exp. 2023 Sep 30;99:100717. doi: 10.1016/j.curtheres.2023.100717. PMID: 37869401; PMCID: PMC10589763.