Associate Professor
Christian Medical College Vellore, Ida Scudder Road, Vellore – 632004, Tamil Nadu, India
Manesh A, Mani RS, Pichamuthu K, Jagannati M, Mathew V, Karthik R, Abraham OC, Chacko G, Varghese GM. Case Report: Failure of Therapeutic Coma in Rabies Encephalitis. Am J Trop Med Hyg. 2018 Jan;98(1):207-210. doi: 10.4269/ajtmh.17-0153. Epub 2018 Jan 1. PMID: 29141755; PMCID: PMC5928693.
Manesh A, Barnabas R, Mani S, Karthik R, Abraham OC, Chacko G, Kannangai R, Varghese GM. Symptomatic HIV CNS viral escape among patients on effective cART. Int J Infect Dis. 2019 Jul;84:39-43. doi: 10.1016/j.ijid.2019.03.033. Epub 2019 Apr 2. PMID: 30951880. Link
Rupali P, Mannam S, Bella A, John L, Rajkumar S, Clarence P, Pulimood SA, Samuel P, Karthik R, Abraham OC, Mathai D. Risk factors for mortality in a south Indian population on generic antiretroviral therapy. J Assoc Physicians India. 2012 Dec;60:11-4. PMID: 23781664.
Sadashiv MS, Rupali P, Manesh A, Kannangai R, Abraham OC, Pulimood SA, Karthik R, Rajkumar S, Thomas K. Risk Factors of Clinical and Immunological Failure in South Indian Cohort on Generic Antiretroviral Therapy. J Assoc Physicians India. 2017 Dec;65(12):34-39. PMID: 29327520.
Varghese GM, John R, Manesh A, Karthik R, Abraham OC. Clinical management of COVID-19. Indian J Med Res. 2020 May;151(5):401-410. doi: 10.4103/ijmr.IJMR_957_20. PMID: 32611911; PMCID: PMC7530435. Link
Mathuram, A. J., Singh, S., Abraham, O. C., Zachariah, A., Rupali, P., Varghese, G. M., Karthik, R. and Clarence, P. Antiretroviral therapy under the national program: Experience of a single large centre in Southern India Journal of Clinical and Diagnostic Research; 2018, 12 (3): OC05-OC07
Manesh A, Mani RS, Pichamuthu K, Jagannati M, Mathew V, Karthik R, Abraham OC, Chacko G, Varghese GM. Case Report: Failure of Therapeutic Coma in Rabies Encephalitis. Am J Trop Med Hyg. 2018 Jan;98(1):207-210. doi: 10.4269/ajtmh.17-0153. Epub 2018 Jan 1. PMID: 29141755; PMCID: PMC5928693.
Manesh A, Barnabas R, Mani S, Karthik R, Abraham OC, Chacko G, Kannangai R, Varghese GM. Symptomatic HIV CNS viral escape among patients on effective cART. Int J Infect Dis. 2019 Jul;84:39-43. doi: 10.1016/j.ijid.2019.03.033. Epub 2019 Apr 2. PMID: 30951880. Link
Rupali P, Mannam S, Bella A, John L, Rajkumar S, Clarence P, Pulimood SA, Samuel P, Karthik R, Abraham OC, Mathai D. Risk factors for mortality in a south Indian population on generic antiretroviral therapy. J Assoc Physicians India. 2012 Dec;60:11-4. PMID: 23781664.
Sadashiv MS, Rupali P, Manesh A, Kannangai R, Abraham OC, Pulimood SA, Karthik R, Rajkumar S, Thomas K. Risk Factors of Clinical and Immunological Failure in South Indian Cohort on Generic Antiretroviral Therapy. J Assoc Physicians India. 2017 Dec;65(12):34-39. PMID: 29327520.
Varghese GM, John R, Manesh A, Karthik R, Abraham OC. Clinical management of COVID-19. Indian J Med Res. 2020 May;151(5):401-410. doi: 10.4103/ijmr.IJMR_957_20. PMID: 32611911; PMCID: PMC7530435. Link
Mathuram, A. J., Singh, S., Abraham, O. C., Zachariah, A., Rupali, P., Varghese, G. M., Karthik, R. and Clarence, P. Antiretroviral therapy under the national program: Experience of a single large centre in Southern India Journal of Clinical and Diagnostic Research; 2018, 12 (3): OC05-OC07
Karthik R, Pancharatnam P, Balaji V. Fatal Chromobacterium violaceum septicemia in a South Indian adult. J Infect Dev Ctries. 2012 Oct 19;6(10):751-5. doi: 10.3855/jidc.1866. PMID: 23103899.
Thomas K, Peter JV, Christina J, Jagadish AR, Rajan A, Lionel P, Jeyaseelan L, Yadav B, John G, Pichamuthu K, Chacko B, Pari P, Murugesan T, Rajendran K, John A, Sathyendra S, Iyyadurai R, Jasmine S, Karthik R, Mathuram A, Hansdak SG, Abhilash KP, Kumar S, John KR, Sudarsanam TD. Cost-utility in medical intensive care patients. Rationalizing ongoing care and timing of discharge from intensive care. Ann Am Thorac Soc. 2015 Jul;12(7):1058-65. doi: 10.1513/AnnalsATS.201411-527OC. PMID: 26011090.
Divyashree S, Karthik R, Prabhu K, Chacko G. Pituitary aspergillosis - A report and review of the literature. Neurol India. 2018 Jul-Aug;66(4):1176-1178. doi: 10.4103/0028-3886.236975. PMID: 30038117
Karthik RK, Sudarsanam TD. An unusual cause of empyema thoracis. Indian J Med Sci. 2009 Jan;63(1):30-2. PMID: 19346638. Link
Balaji V, Rajiv K, Abraham OC. Burkholderia pseudomallei recovered in an HIV-positive individual. Indian J Med Sci. 2008 Nov;62(11):456-8. doi: 10.4103/0019-5359.48457. PMID: 19265236.
Thuppal SV, Wanke CA, Noubary F, Cohen JT, Mwamburi M, Ooriapdickal AC, Muliyil J, Kang G, Varghese GM, Rupali P, Karthik R, Sathasivam R, Clarance P, Pulimood SA, Peter D, George L. Toxicity and clinical outcomes in patients with HIV on zidovudine and tenofovir based regimens: a retrospective cohort study. Trans R Soc Trop Med Hyg. 2015 Jun;109(6):379-85. doi: 10.1093/trstmh/trv016. Epub 2015 Mar 15. PMID: 25778734; PMCID: PMC4542851.
Chakrabarti A, Kaur H, Savio J, Rudramurthy SM, Patel A, Shastri P, Pamidimukkala U, Karthik R, Bhattacharya S, Kindo AJ, Bhattacharya P, Todi S, Gopalakrishan R, Singh P, Pandey A, Agarwal R. Epidemiology and clinical outcomes of invasive mould infections in Indian intensive care units (FISF study). J Crit Care. 2019 Jun;51:64-70. doi: 10.1016/j.jcrc.2019.02.005. Epub 2019 Feb 5. PMID: 30769292.
Mitra S, Karthik R, Balaji V, George IA, Kapil A, Abraham OC. Quinolone-resistant Salmonella enterica Serovar typhi presenting as acute fulminant hepatitis. J Assoc Physicians India. 2009 Apr;57:338-9. PMID: 19702041.
Arockiaraj J, Karthik R, Michael JS, Amritanand R, David KS, Krishnan V, Sundararaj GD. 'Need of the Hour': Early Diagnosis and Management of Multidrug Resistant Tuberculosis of the Spine: An Analysis of 30 Patients from a "High Multidrug Resistant Tuberculosis Burden" Country. Asian Spine J. 2019 Apr;13(2):265-271. doi: 10.31616/asj.2018.0073. Epub 2019 Jan 24. PMID: 30669824; PMCID: PMC6454281.
Arockiaraj J, Karthik R, Michael JS, Amritanand R, David KS, Krishnan V, Sundararaj GD. 'Need of the Hour': Early Diagnosis and Management of Multidrug Resistant Tuberculosis of the Spine: An Analysis of 30 Patients from a "High Multidrug Resistant Tuberculosis Burden" Country. Asian Spine J. 2019 Apr;13(2):265-271. doi: 10.31616/asj.2018.0073. Epub 2019 Jan 24. PMID: 30669824; PMCID: PMC6454281.
Ramakrishna K, Peter JV, Karthik G, Abraham AM, Surekha V, Karthik R, Chacko B. Influenza A (H1N1) 2009 pandemic: was there a difference in the two waves in patients requiring admission to the intensive-care unit? Clin Microbiol Infect. 2011 Sep;17(9):1355-8. doi: 10.1111/j.1469-0691.2011.03584.x. Epub 2011 Jun 17. PMID: 21679373. Link
Bhanuprasad K, Manesh A, Devasagayam E, Varghese L, Cherian LM, Kurien R, Karthik R, Deodhar D, Vanjare H, Peter J, Michael JS, Thomas M, Samuel P, Varghese GM. Risk factors associated with the mucormycosis epidemic during the COVID-19 pandemic. Int J Infect Dis. 2021 Oct;111:267-270. doi: 10.1016/j.ijid.2021.08.037. Epub 2021 Aug 24. PMID: 34450284; PMCID: PMC8383616.
Manesh A, Mani RS, Pichamuthu K, Jagannati M, Mathew V, Karthik R, Abraham OC, Chacko G, Varghese GM. Case Report: Failure of Therapeutic Coma in Rabies Encephalitis. Am J Trop Med Hyg. 2018 Jan;98(1):207-210. doi: 10.4269/ajtmh.17-0153. Epub 2018 Jan 1. PMID: 29141755; PMCID: PMC5928693.
Hernandez AL, Karthik R, Sivasubramanian M, Raghavendran A, Gnanamony M, Lensing S, Lee JY, Kannangai R, Abraham P, Mathai D, Palefsky JM. Prevalence of Anal HPV Infection Among HIV-Positive Men Who Have Sex With Men in India. J Acquir Immune Defic Syndr. 2016 Apr 1;71(4):437-43. doi: 10.1097/QAI.0000000000000855. PMID: 26379067; PMCID: PMC4939069. Link
Arockiaraj J, Karthik R, Jeyaraj V, Amritanand R, Krishnan V, David KS, Sundararaj GD. Non-Caseating Granulomatous Infective Spondylitis: Melioidotic Spondylitis. Asian Spine J. 2016 Dec;10(6):1065-1071. doi: 10.4184/asj.2016.10.6.1065. Epub 2016 Dec 8. PMID: 27994782; PMCID: PMC5164996. Link
Murugesan M, Mathews P, Paul H, Karthik R, Mammen JJ, Rupali P. Protective effect conferred by prior infection and vaccination on COVID-19 in a healthcare worker cohort in South India. PLoS One. 2022 May 20;17(5):e0268797. doi: 10.1371/journal.pone.0268797. PMID: 35594270; PMCID: PMC9122209.
Murugesan M, Venkatesan P, Ramasamy J, Samuel P, Karthik R, Rose W, Rupali P. Transmission Dynamics of COVID-19 and Utility of Contact Tracing in Risk Assessment of Health-Care Worker Exposure during COVID-19 Pandemic. Indian J Community Med. 2022 Jan-Mar;47(1):82-86. doi: 10.4103/ijcm.ijcm_1097_21. Epub 2022 Mar 16. PMID: 35368479; PMCID: PMC8971878.
Kaswala C, Schmiedel Y, Kundu D, George MM, Dayanand D, Devasagayam E, Manesh S A, Kumar SS, Michael JS, Ninan MM, Chacko G, Zachariah A, Sathyendra S, Hansdak SG, Iyadurai R, Christopher DJ, Gupta R, Karthik R, Abraham OC, Varghese GM. Accuracy of Gene Xpert MTB/RIF Ultra for the diagnosis of tuberculosis in adult patients: A retrospective cohort study. Int J Infect Dis. 2022 Jul 7:S1201-9712(22)00410-6. doi: 10.1016/j.ijid.2022.07.016. Epub ahead of print. PMID: 35811084. Link
Tharakan SJ, Peter Cv D, Karthik R, Rupa V, Rose W, Thomas M, Manuel M, Rupali P, Pulimood S, Rao Ajjampur SS. Case Report: A Single-Center Case Series on Skin Manifestations of Leishmaniasis from a Non-Endemic State in Southern India. Am J Trop Med Hyg. 2020 Dec 29;104(3):928-933. doi: 10.4269/ajtmh.20-0938. PMID: 33377447; PMCID: PMC7941818.
Raghavendran A, Hernandez AL, Lensing S, Gnanamony M, Karthik R, Sivasubramanian M, Kannangai R, Abraham P, Mathai D, Palefsky JM. Genital Human Papillomavirus Infection in Indian HIV-Seropositive Men Who Have Sex With Men. Sex Transm Dis. 2017 Mar;44(3):173-180. doi: 10.1097/OLQ.0000000000000564. PMID: 28178116; PMCID: PMC5302848.
Manesh A, Devasagayam E, Bhanuprasad K, Mathew SK, Karthik R, Mathew BS, Varghese GM. Efficacy of Crushed Delayed-Release Posaconazole Tablets in Rhino-Orbito-Cerebral Mucormycosis. Antimicrob Agents Chemother. 2022 Dec 20;66(12):e0108522. doi: 10.1128/aac.01085-22. Epub 2022 Nov 15. PMID: 36377934; PMCID: PMC9765161.
Divyashree S, Karthik R, Prabhu K, Chacko G. Pituitary aspergillosis - A report and review of the literature. Neurol India. 2018 Jul-Aug;66(4):1176-1178. doi: 10.4103/0028-3886.236975. PMID: 30038117. Link
Manesh A, Shankar C, George MM, Jasrotia DS, Lal B, George B, Mathews V, Eapen CE, Joseph P, Subramani K, Rao S, Peter JV, Chacko B, Zachariah A, Sathyendra S, Hansdak SG, Abraham OC, Iyadurai R, Vijayakumar S, Karthik R, Marwick CA, Parcell BJ, Gilbert IH, Veeraraghavan B, Varghese GM. Clinical and Genomic Evolution of Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections over Two Time Periods at a Tertiary Care Hospital in South India: A Prospective Cohort Study. Infect Dis Ther. 2023 May;12(5):1319-1335. doi: 10.1007/s40121-023-00803-3. Epub 2023 Apr 16. PMID: 37062023; PMCID: PMC10229510.
Kaswala C, Schmiedel Y, Kundu D, George MM, Dayanand D, Devasagayam E, S AM, Kumar SS, Michael JS, Ninan MM, Chacko G, Zachariah A, Sathyendra S, Hansdak SG, Iyadurai R, Christopher DJ, Gupta R, Karthik R, Abraham OC, Varghese GM. Accuracy of Xpert MTB/RIF Ultra for the diagnosis of tuberculosis in adult patients: a retrospective cohort study. Int J Infect Dis. 2022 Sep;122:566-568. doi: 10.1016/j.ijid.2022.07.016. Epub 2022 Jul 8. PMID: 35811084.
Solaimalai D, Gupta A, George L, Manesh A, Karthik R, Sathishkumar D, Peter CVD, Varghese GM, Pulimood SA, Kannangai R, Prakash JA. Upward trends of syphilis in the non-pregnant adults: A six-year report on clinical and epidemiological profile of syphilis from a tertiary care center, India. Front Public Health. 2022 Jul 26;10:908591. doi: 10.3389/fpubh.2022.908591. PMID: 35958862; PMCID: PMC9359669.
Hernandez AL, Karthik R, Sivasubramanian M, Raghavendran A, Lensing S, Lee JY, Abraham P, Mathai D, Palefsky JM. Prevalence of oral human papillomavirus infection among Indian HIV-positive men who have sex with men: a cross-sectional study. BMC Infect Dis. 2021 Jul 12;21(1):675. doi: 10.1186/s12879-021-06301-6. PMID: 34247583; PMCID: PMC8274002.
Manesh A, Devasagayam E, Bhanuprasad K, Varghese L, Kurien R, Cherian LM, Dayanand D, George MM, Kumar SS, Karthik R, Vanjare H, Peter J, Michael JS, Thomas M, Mathew BS, Samuel P, Peerawaranun P, Mukaka M, Rupa V, Varghese GM. Short intravenous amphotericin B followed by oral posaconazole using a simple, stratified treatment approach for diabetes or COVID-19-associated rhino-orbito-cerebral mucormycosis: a prospective cohort study. Clin Microbiol Infect. 2023 Oct;29(10):1298-1305. doi: 10.1016/j.cmi.2023.06.017. Epub 2023 Jun 20. PMID: 37348653; PMCID: PMC10281032.
Kundu D, Gautam P, Dayanand D, Gunasekaran K, Manesh A, Sebastian M, Abhilash KPP, Zachariah A, George T, Sathyendra S, Hansdak SG, Abraham OC, Iyadurai R, Thangakunam B, Gupta R, Karthik R, Moorthy M, Varghese GM. The role and diagnostic accuracy of serology for COVID-19. BMC Infect Dis. 2022 Apr 19;22(1):390. doi: 10.1186/s12879-022-0736-1y. PMID: 35439957; PMCID: PMC9017961. Link
Priya T T, Jacob JJ, M Y, Karthik R, Iyadurai R, G K, Devi B Y, Walia K, Veeraraghavan B. Is it time to move on to gene-based Salmonella typing: Evidence and implications. Indian J Med Microbiol. 2023 Jul-Aug;44:100359. doi: 10.1016/j.ijmmb.2023.02.002. Epub 2023 May 11. PMID: 37356840.
Bhanuprasad K, Manesh A, Devasagayam E, Varghese L, Cherian LM, Kurien R, Karthik R, Deodhar D, Vanjare H, Peter J, Michael JS, Thomas M, Samuel P, Varghese GM. Risk factors associated with the mucormycosis epidemic during the COVID-19 pandemic. Int J Infect Dis. 2021 Oct;111:267-270. doi: 10.1016/j.ijid.2021.08.037. Epub 2021 Aug 24. PMID: 34450284; PMCID: PMC8383616.
Manesh A, Mani RS, Pichamuthu K, Jagannati M, Mathew V, Karthik R, Abraham OC, Chacko G, Varghese GM. Case Report: Failure of Therapeutic Coma in Rabies Encephalitis. Am J Trop Med Hyg. 2018 Jan;98(1):207-210. doi: 10.4269/ajtmh.17-0153. Epub 2018 Jan 1. PMID: 29141755; PMCID: PMC5928693.
S AM, Gautam P, D SSK, Mannam P, Jasper A, Gunasekaran K, Thomas NC, Benjamin RN, Inbaraj LR, Devasagayam E, George MM, Karthik R, Abraham OC, Vanjare HA, Sivadasan A, Prabhakar AT, Jonathan E, Michael JS, Samuel P, Varghese GM. Effectiveness of adjunctive high dose infliximab therapy to improve disability free survival among patients with severe CNS tuberculosis: a matched retrospective cohort study. Clin Infect Dis. 2023 Jul 5:ciad401. doi: 10.1093/cid/ciad401. Epub ahead of print. PMID: 37405816. Link
Varghese GM, John R, Manesh A, Karthik R, Abraham OC. Authors' response. Indian J Med Res. 2020 Jul & Aug;152(1 & 2):151-152. doi: 10.4103/0971-5916.294037. PMID: 32883920; PMCID: PMC7853270.
S B MJ, Chacko B, Selvarajan S, Peter JV, Geevar T, Dave RG, Georgy JT, Zachariah A, George T, Sathyendra S, Hansdak SG, Krishnaswami RK, Thangakunam B, Gupta R, Karuppusami R, Nair SC, Srivastava A. Biomarkers of coagulation, endothelial, platelet function, and fibrinolysis in patients with COVID-19: a prospective study. Sci Rep. 2024 Jan 23;14(1):2011. doi: 10.1038/s41598-024-51908-9. PMID: 38263377; PMCID: PMC10805716.
Manesh A, Gautam P, Kumar D SS, Mannam P, Jasper A, Gunasekaran K, Thomas NC, Benjamin RN, Inbaraj LR, Devasagayam E, George MM, Karthik R, Abraham OC, Vanjare HA, Sivadasan A, Appaswamy PT, Jonathan E, Michael JS, Samuel P, Varghese GM. Effectiveness of Adjunctive High-Dose Infliximab Therapy to Improve Disability-Free Survival Among Patients With Severe Central Nervous System Tuberculosis: A Matched Retrospective Cohort Study. Clin Infect Dis. 2023 Nov 17;77(10):1460-1467. doi: 10.1093/cid/ciad401. PMID: 37405816.
Manesh, Abi et al. “Primary odontogenic onset invasive mucormycosis-an under recognized clinical entity.” Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases vol. 29,8 (2023): 1086.e1-1086.e5. doi:10.1016/j.cmi.2023.05.002