Professor
Christian Medical College Vellore, Ida Scudder Road, Vellore – 632004, Tamil Nadu, India
David S, Nair SC, Singh GS, Alex AA, Ganesan S, Palani HK, Balasundaram N, Lakshmi KM, Joshi A, Kannan S, Korula A, Nambiatheyil Aboobacker F, Abraham A, George B, Apte SJ, Srivastava A, Mathews V. Prevalence of FVIII inhibitors in severe haemophilia A patients: Effect of treatment and genetic factors in an Indian population. Haemophilia. 2019 Jan;25(1):67-74. doi: 10.1111/hae.13633. Epub 2018 Nov 14. PMID: 30427567.
Abbas S, Kini A, Srivastava VM, M MT, Nair SC, Abraham A, Mathews V, George B, Kumar S, Venkatraman A, Srivastava A. Coexistence of aberrant hematopoietic and stromal elements in myelodysplastic syndromes. Blood Cells Mol Dis. 2017 Jul;66:37-46. doi: 10.1016/j.bcmd.2017.08.004. Epub 2017 Aug 9. PMID: 28822917. Link
Sumitha E, Jayandharan GR, Arora N, Abraham A, David S, Devi GS, Shenbagapriya P, Nair SC, George B, Mathews V, Chandy M, Viswabandya A, Srivastava A. Molecular basis of quantitative fibrinogen disorders in 27 patients from India. Haemophilia. 2013 Jul;19(4):611-8. doi: 10.1111/hae.12143. Epub 2013 Apr 8. PMID: 23560673. Link
David S, Jayandharan GR, Abraham A, Jacob RR, Devi GS, Patkar N, Shaji RV, Nair SC, Viswabandya A, Ahmed R, George B, Mathews V, Chandy M, Srivastava A. Molecular basis of Wiskott-Aldrich syndrome in patients from India. Eur J Haematol. 2012 Oct;89(4):356-60. doi: 10.1111/j.1600-0609.2012.01818.x. Epub 2012 Jul 14. PMID: 22679904. Link
Viswabandya A, Baidya S, Nair SC, Abraham A, George B, Mathews V, Chandy M, Srivastava A. Correlating clinical manifestations with factor levels in rare bleeding disorders: a report from Southern India. Haemophilia. 2012 May;18(3):e195-200. doi: 10.1111/j.1365-2516.2011.02730.x. Epub 2012 Jan 4. PMID: 22221743. Link
Arora N, Nair S, Pai R, Nair S, Ahmed R, Abraham A, Viswabandya A, George B, Balasubramanian P, Srivastava A, Mathews V. V-raf murine sarcoma viral oncogene homolog B (BRAF) mutations in hairy cell leukaemia. Indian J Pathol Microbiol. 2015 Jan-Mar;58(1):62-5. doi: 10.4103/0377-4929.151190. PMID: 25673595. Link
David S, Nair SC, Singh GS, Alex AA, Ganesan S, Palani HK, Balasundaram N, Lakshmi KM, Joshi A, Kannan S, Korula A, Nambiatheyil Aboobacker F, Abraham A, George B, Apte SJ, Srivastava A, Mathews V. Prevalence of FVIII inhibitors in severe haemophilia A patients: Effect of treatment and genetic factors in an Indian population. Haemophilia. 2019 Jan;25(1):67-74. doi: 10.1111/hae.13633. Epub 2018 Nov 14. PMID: 30427567.
Abbas S, Kini A, Srivastava VM, M MT, Nair SC, Abraham A, Mathews V, George B, Kumar S, Venkatraman A, Srivastava A. Coexistence of aberrant hematopoietic and stromal elements in myelodysplastic syndromes. Blood Cells Mol Dis. 2017 Jul;66:37-46. doi: 10.1016/j.bcmd.2017.08.004. Epub 2017 Aug 9. PMID: 28822917. Link
Sumitha E, Jayandharan GR, Arora N, Abraham A, David S, Devi GS, Shenbagapriya P, Nair SC, George B, Mathews V, Chandy M, Viswabandya A, Srivastava A. Molecular basis of quantitative fibrinogen disorders in 27 patients from India. Haemophilia. 2013 Jul;19(4):611-8. doi: 10.1111/hae.12143. Epub 2013 Apr 8. PMID: 23560673. Link
David S, Jayandharan GR, Abraham A, Jacob RR, Devi GS, Patkar N, Shaji RV, Nair SC, Viswabandya A, Ahmed R, George B, Mathews V, Chandy M, Srivastava A. Molecular basis of Wiskott-Aldrich syndrome in patients from India. Eur J Haematol. 2012 Oct;89(4):356-60. doi: 10.1111/j.1600-0609.2012.01818.x. Epub 2012 Jul 14. PMID: 22679904. Link
Viswabandya A, Baidya S, Nair SC, Abraham A, George B, Mathews V, Chandy M, Srivastava A. Correlating clinical manifestations with factor levels in rare bleeding disorders: a report from Southern India. Haemophilia. 2012 May;18(3):e195-200. doi: 10.1111/j.1365-2516.2011.02730.x. Epub 2012 Jan 4. PMID: 22221743. Link
Arora N, Nair S, Pai R, Nair S, Ahmed R, Abraham A, Viswabandya A, George B, Balasubramanian P, Srivastava A, Mathews V. V-raf murine sarcoma viral oncogene homolog B (BRAF) mutations in hairy cell leukaemia. Indian J Pathol Microbiol. 2015 Jan-Mar;58(1):62-5. doi: 10.4103/0377-4929.151190. PMID: 25673595. Link
Chendamarai E, Balasubramanian P, George B, Viswabandya A, Abraham A, Ahmed R, Alex AA, Ganesan S, Lakshmi KM, Sitaram U, Nair SC, Chandy M, Janet NB, Srivastava VM, Srivastava A, Mathews V. Role of minimal residual disease monitoring in acute promyelocytic leukemia treated with arsenic trioxide in frontline therapy. Blood. 2012 Apr 12;119(15):3413-9. doi: 10.1182/blood-2011-11-393264. Epub 2012 Feb 28. PMID: 22374701. Link
Emmanuel A, Selvaraj D, Sen I, Agarwal S, Stephen E, Kota A, Nair SC, Antoniswamy B. D-dimer levels in patients with thromboangiitis obliterans. Natl Med J India. 2019 May-Jun;32(3):134-136. doi: 10.4103/0970-258X.278685. PMID: 32129304.
Sumitha E, Jayandharan GR, David S, Jacob RR, Sankari Devi G, Bargavi B, Shenbagapriya S, Nair SC, Abraham A, George B, Viswabandya A, Mathews V, Chandy M, Srivastava A. Molecular basis of Bernard-Soulier syndrome in 27 patients from India. J Thromb Haemost. 2011 Aug;9(8):1590-8. doi: 10.1111/j.1538-7836.2011.04417.x. PMID: 21699652. Link
Chapla A, Jayandharan GR, Sumitha E, Sankari Devi G, Shenbagapriya P, Nair SC, Viswabandya A, George B, Mathews V, Srivastava A. Molecular basis of hereditary factor V deficiency in India: identification of four novel mutations and their genotype-phenotype correlation. Thromb Haemost. 2011 Jun;105(6):1120-3. doi: 10.1160/TH10-11-0767. Epub 2011 Apr 20. PMID: 21647534. Link
Vinayak Shulda, Sukesh Chandran, Shashi Varma, Navin Lal, Sushtl M. Chandt, Roy John Korula Primary Bronchial Leiomyosarcoma Ind_Jl_of Thoracic_and Cardio_Vas_Surg_Vol-9_No-2_111-113_Dec-1993
Jayandharan GR, Nair SC, Poonnoose PM, Thomas R, John J, Keshav SK, Cherian RS, Devadarishini M, Lakshmi KM, Shaji RV, Viswabandya A, George B, Mathews V, Chandy M, Srivastava A. Polymorphism in factor VII gene modifies phenotype of severe haemophilia. Haemophilia. 2009 Nov;15(6):1228-36. doi: 10.1111/j.1365-2516.2009.02080.x. Epub 2009 Aug 16. PMID: 19686262. Link
Viswabandya A, Mathews V, George B, Nair SC, Baidya S, Mammen JJ, Chandy M, Srivastava A. Successful surgical haemostasis in patients with von Willebrand disease with Koate DVI. Haemophilia. 2008 Jul;14(4):763-7. doi: 10.1111/j.1365-2516.2008.01755.x. Epub 2008 Apr 24. PMID: 18445014. Link
Viswabandya A, Baidya S, Nair SC, Lakshmi KM, Mathews V, George B, Chandy M, Srivastava A. Clinical manifestations of combined factor V and VIII deficiency: a series of 37 cases from a single center in India. Am J Hematol. 2010 Jul;85(7):538-9. doi: 10.1002/ajh.21741. PMID: 20575023; PMCID: PMC7159400.
Bankar A, Korula A, Kulkarni UP, Devasia AJ, Na F, Lionel S, Abraham A, Balasubramanian P, Janet NB, Nair SC, S S, Jeyaseelan V, N J, Prasad J, George B, Mathews V. Resource utilization and cost effectiveness of treating acute promyelocytic leukaemia using generic arsenic trioxide. Br J Haematol. 2020 Apr;189(2):269-278. doi: 10.1111/bjh.16343. Epub 2019 Dec 21. PMID: 31863602.
Nair SC, Geevar T, Dave RG. Plasma Coagulation Tests for Detection of Antiphospholipid Antibodies: What's Good, and What Might Be Improved? Indian J Hematol Blood Transfus. 2019 Jul;35(3):407-408. doi: 10.1007/s12288-019-01151-4. Epub 2019 Jul 10. PMID: 31388248; PMCID: PMC6646623.
Jayandharan GR, Viswabandya A, Baidya S, Nair SC, George B, Mathews V, Chandy M, Srivastava A. Mutations in coagulation factor XIII A gene in eight unrelated Indians. Five novel mutations identified by a novel PCR-CSGE approach. Thromb Haemost. 2006 Mar;95(3):551-6. doi: 10.1160/TH05-09-0617. PMID: 16525586. Link
Dave RG, Geevar T, Mammen JJ, Vijayan R, Mahasampath G, Nair SC. Clinical utility of activated partial thromboplastin time clot waveform analysis and thrombin generation test in the evaluation of bleeding phenotype in Hemophilia A. Indian J Pathol Microbiol. 2021 Jan-Mar;64(1):117-122. doi: 10.4103/IJPM.IJPM_336_19. PMID: 33433420.
Mathews V, Viswabandya A, Baidya S, George B, Nair S, Chandy M, Srivastava A. Surgery for hemophilia in developing countries. Semin Thromb Hemost. 2005 Nov;31(5):538-43. doi: 10.1055/s-2005-922225. PMID: 16276462. Link
Naina HV, Nair SC, Daniel D, George B, Chandy M. Asymptomatic constitutional macrothrombocytopenia among West Bengal blood donors. Am J Med. 2002 Jun 15;112(9):742-3. doi: 10.1016/s0002-9343(02)01114-2. PMID: 12079722. Link
Olson JD, Jennings I, Meijer P, Bon C, Bonar R, Favaloro EJ, Higgins RA, Keeney M, Mammen J, Marlar RA, Meley R, Nair SC, Nichols WL, Raby A, Reverter JC, Srivastava A, Walker I. Lack of grading agreement among international hemostasis external quality assessment programs. Blood Coagul Fibrinolysis. 2018 Jan;29(1):111-119. doi: 10.1097/MBC.0000000000000690. PMID: 29232255; PMCID: PMC5794233.
Fouzia NA, Sharma V, Ganesan S, Palani HK, Balasundaram N, David S, Kulkarni UP, Korula A, Devasia AJ, Nair SC, Janet NB, Abraham A, Mani T, Lakshmanan J, Balasubramanian P, George B, Mathews V. Management of relapse in acute promyelocytic leukaemia treated with up-front arsenic trioxide-based regimens. Br J Haematol. 2021 Jan;192(2):292-299. doi: 10.1111/bjh.17221. Epub 2020 Nov 20. PMID: 33216980; PMCID: PMC7894296.
Lee VN, Srivastava A, Nithyananth M, Kumar P, Cherian VM, Viswabandya A, Mathews V, George B, Venkatesh K, Nair SC, Chandy M, Sundararaj GD. Fracture neck of femur in haemophilia A - experience from a cohort of 11 patients from a tertiary centre in India. Haemophilia. 2007 Jul;13(4):391-4. doi: 10.1111/j.1365-2516.2007.01448.x. PMID: 17610554. Link
Kuprash AD, Shibeko AM, Vijay R, Nair SC, Srivastava A, Ataullakhanov FI, Panteleev MA, Balandina AN. Sensitivity and Robustness of Spatially Dependent Thrombin Generation and Fibrin Clot Propagation. Biophys J. 2018 Dec 18;115(12):2461-2473. doi: 10.1016/j.bpj.2018.11.009. Epub 2018 Nov 14. PMID: 30514632; PMCID: PMC6301986. Link
Soonam John, Nitty Skariah Mathews, Sukesh Chandran Nair. Early prediction of coagulopathy in acquired bleeding disorders - revisited using rotational thromboelastometry. International Journal of Contemporary Medical Research 2019;6(1):A1-A5. Link
Jayandharan G, Viswabandya A, Baidya S, Nair SC, Shaji RV, George B, Chandy M, Srivastava A. Six novel mutations including triple heterozygosity for Phe31Ser, 514delT and 516T-->G factor X gene mutations are responsible for congenital factor X deficiency in patients of Nepali and Indian origin. J Thromb Haemost. 2005 Jul;3(7):1482-7. doi: 10.1111/j.1538-7836.2005.01339.x. Epub 2005 May 9. PMID: 15892863. Link
Bhaskar A, Nair S, Ta T. Cell based model of haemostasis. Current Medical Issues Journal. 2016 04/01;14:53-8.
Abbas S, Kumar S, Srivastava VM, Therese M M, Nair SC, Abraham A, Mathews V, George B, Srivastava A. Heterogeneity of Mesenchymal Stromal Cells in Myelodysplastic Syndrome-with Multilineage Dysplasia (MDS-MLD). Indian J Hematol Blood Transfus. 2019 Apr;35(2):223-232. doi: 10.1007/s12288-018-1062-6. Epub 2019 Jan 1. PMID: 30988556; PMCID: PMC6439082.
Chendamarai E, Ganesan S, Alex AA, Kamath V, Nair SC, Nellickal AJ, Janet NB, Srivastava V, Lakshmi KM, Viswabandya A, Abraham A, Aiyaz M, Mullapudi N, Mugasimangalam R, Padua RA, Chomienne C, Chandy M, Srivastava A, George B, Balasubramanian P, Mathews V. Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance. PLoS One. 2015 Mar 30;10(3):e0121912. doi: 10.1371/journal.pone.0121912. PMID: 25822503; PMCID: PMC4378855. Link
Ninan K F, Iyadurai R, Varghese JK, Geevar T, Nair SC, Yadav B, Carey RAB, Sadiq J M, Koshy M, Ralph R, Peter JV. Thromboelastograph:A prognostic marker in sepsis with organ dysfunction without overt bleeding. J Crit Care. 2021 Oct;65:177-183. doi: 10.1016/j.jcrc.2021.06.005. Epub 2021 Jun 23. PMID: 34171693.
Kitchen S, Adcock DM, Dauer R, Kristoffersen AH, Lippi G, Mackie I, Marlar RA, Nair S. International Council for Standardization in Haematology (ICSH) recommendations for processing of blood samples for coagulation testing. Int J Lab Hematol. 2021 Dec;43(6):1272-1283. doi: 10.1111/ijlh.13702. Epub 2021 Sep 27. PMID: 34581008.
Dunkley S, Lam JCM, John MJ, Wong RSM, Tran H, Yang R, Nair SC, Shima M, Street A, Srivastava A. Principles of haemophilia care: The asia pacific perspective. Response. Haemophilia. 2018 Jul;24(4):e243-e244. doi: 10.1111/hae.13522. Epub 2018 Jun 14. PMID: 29901827. Link
Kitchen S, Adcock DM, Dauer R, Kristoffersen AH, Lippi G, Mackie I, Marlar RA, Nair S. International Council for Standardization in Haematology (ICSH) recommendations for processing of blood samples for coagulation testing. Int J Lab Hematol. 2021 Sep 27. doi: 10.1111/ijlh.13702. Epub ahead of print. PMID: 34581008. Link
Dave RG, Geevar T, Chellaiya GK, Mammen JJ, Vijayan R, Samuel A, Gowri M, Nair SC. Stability and utility of flow cytometric platelet activation tests: A modality to bridge the gap between diagnostic demand and supply. Platelets. 2022 Feb 28:1-9. doi: 10.1080/09537104.2022.2042232. Epub ahead of print. PMID: 35225160.
Dave RG, Geevar T, Chellaiya GK, Mammen JJ, Vijayan R, Samuel A, Gowri M, Nair SC. Stability and utility of flow cytometric platelet activation tests: A modality to bridge the gap between diagnostic demand and supply. Platelets. 2022 Feb 28:1-9. doi: 10.1080/09537104.2022.2042232. Epub ahead of print. PMID: 35225160.
Dave RG, Padiyar S, Mathew J, Nair SC. Unusual Morphological and Automated Hematology Analyzer Features in 3 Cases of B-cell Malignancy-associated Type I Cryoglobulinemic Vasculitis. Indian J Hematol Blood Transfus. 2021 Oct;37(4):658-663. doi: 10.1007/s12288-021-01398-w. Epub 2021 Jan 27. PMID: 34744348; PMCID: PMC8523623.
Desai SR, Korula A, Kulkarni UP, Menon AA, Ramachandran SV, Sindhuvi E, Nellickal AJ, Nair SC, George B. Sitosterolemia: Four Cases of an Uncommon Cause of Hemolytic Anemia (Mediterranean Stomatocytosis with Macrothrombocytopenia). Indian J Hematol Blood Transfus. 2021 Jan;37(1):157-161. doi: 10.1007/s12288-020-01346-0. Epub 2020 Oct 22. PMID: 33707850; PMCID: PMC7900322. Link
Hazra D, Sen I, Stephen E, Agarwal S, Nair SC, Mammen J. Evaluation of Factor VIII as a Risk Factor in Indian Patients with DVT. Surg Res Pract. 2015;2015:307879. doi: 10.1155/2015/307879. Epub 2015 Sep 1. PMID: 26421318; PMCID: PMC4569765.
Geevar T, Dave RG, Mathews NS, Kumar S, Mammen JJ, Vijayan R, Aboobacker FN, Abraham A, Srivastava A, Nair SC. Laboratory characterization of obligate carriers of type 3 von Willebrand disease with a potential role for Platelet Function Analyzer (PFA-200). Int J Lab Hematol. 2022 Jan 5. doi: 10.1111/ijlh.13787. Epub ahead of print. PMID: 34986515.
Nair SC, Arora N, Jain S, Inbakumar D, Mammen J, Sitaram U. Mean reticulocyte volume enhances the utility of red cell mean sphered cell volume in differentiating peripheral blood spherocytes of hereditary spherocytosis from other causes. Indian J Pathol Microbiol. 2015 Jul-Sep;58(3):307-9. doi: 10.4103/0377-4929.162836. PMID: 26275251.
Kulkarni UP, Selvarajan S, Lionel S, Prakash MA, Palani HK, Balasundaram N, Venkataraman A, Korula A, Devasia AJ, Fouzia NA, Janet NB, Nair SC, Abraham A, Mani T, Lakshmanan J, Arunachalam AK, Balasubramanian P, George B, Mathews V. Real world data with concurrent retinoic acid and arsenic trioxide for the treatment of acute promyelocytic leukemia. Blood Cancer J. 2022 Jan 31;12(1):22. doi: 10.1038/s41408-022-00619-3. PMID: 35102152; PMCID: PMC8803919. Link
Sen I, Stephen E, Agarwal S, Rebekah G, Nair SC. Analytical performance of a point-of-care device in monitoring patients on oral anticoagulation with vitamin K antagonists. Phlebology. 2016 Oct;31(9):660-7. doi: 10.1177/0268355515608569. Epub 2015 Sep 27. PMID: 26415605.
Goel A, Nair SC, Viswabandya A, Masilamani VP, Rao SV, George A, Regi A, Jose R, Zachariah U, Subramani K, Eapen CE, Chandy G. Preliminary experience with use of recombinant activated factor VII to control postpartum hemorrhage in acute fatty liver of pregnancy and other pregnancy-related liver disorders. Indian J Gastroenterol. 2013 Jul;32(4):268-71. doi: 10.1007/s12664-013-0315-4. Epub 2013 Mar 10. PMID: 23475547.
Mariappan R, Kumar S, Raju K, Daniel D, Nair SC, Subramani S. Comparing two techniques of performing an epidural catheter-assisted epidural blood patch using a 20 ml syringe versus a 5 ml syringe and its effect on clotting time, the strength of clot retraction and haemolysis – A prospective in vitro study (EC-EBP study). Indian Journal of Anaesthesia 2023;67(6):544-7. Link
Gandhi A, Görlinger K, Nair SC, Kapoor PM, Trikha A, Mehta Y, Handoo A, Karlekar A, Kotwal J, John J, Apte S, Vohra V, Gupta G, Tiwari AK, Rani A, Singh SA. Patient blood management in India - Review of current practices and feasibility of applying appropriate standard of care guidelines. A position paper by an interdisciplinary expert group. J Anaesthesiol Clin Pharmacol. 2021 Jan-Mar;37(1):3-13. doi: 10.4103/joacp.JOACP_410_20. Epub 2021 Apr 10. PMID: 34103816; PMCID: PMC8174427.
Riddell A, Chuansumrit A, El-Ekiaby M, Nair SC. Diagnostic laboratory for bleeding disorders ensures efficient management of haemorrhagic disorders. Haemophilia. 2016 Jul;22 Suppl 5:90-5. doi: 10.1111/hae.12988. PMID: 27405683.
Sajith KG, Goel A, Ramachandran J, Priya S, Nair SC, Eapen CE. Erythrocytosis as a cause of false increase in prothrombin time and activated partial thromboplastin time. Indian J Gastroenterol. 2013 Sep;32(5):346-7. doi: 10.1007/s12664-012-0277-y. PMID: 23114799.
Sen D, Gadkari RA, Sudha G, Gabriel N, Kumar YS, Selot R, Samuel R, Rajalingam S, Ramya V, Nair SC, Srinivasan N, Srivastava A, Jayandharan GR. Targeted modifications in adeno-associated virus serotype 8 capsid improves its hepatic gene transfer efficiency in vivo. Hum Gene Ther Methods. 2013 Apr;24(2):104-16. doi: 10.1089/hgtb.2012.195. PMID: 23442071; PMCID: PMC3732127.
Dhanasekaran V, Nair SC, Geevar T, Singh S, Mammen JJ. Utility of Cryohemolysis Test in the Diagnosis of Hereditary Spherocytosis. Indian J Hematol Blood Transfus. 2023 Jul;39(3):499-502. doi: 10.1007/s12288-022-01615-0. Epub 2022 Dec 9. PMID: 37304467; PMCID: PMC10247663.
Arpana Palle, Josephine Thomas, Usha Sitaram, Vandana Kamath, Joy J Mammen, Sukesh C Nair; Identifying Myelodysplastic Syndrome Among Patients with Anemia: Neutrophil Characteristics Computed by a Cell Counter (Beckman Coulter LH750), An Effective Screening Tool. Blood 2011; 118 (21): 5027. doi: https://doi.org/10.1182/blood.V118.21.5027.5027
David S, Mathews NS, Singh GS, Korula A, Aboobacker FN, Abraham A, George B, Srivastava A, Mathews V, Nair SC. Evaluation of nonneutralizing antibodies against factor VIII in severe haemophilia A patients from India. Blood Coagul Fibrinolysis. 2019 Oct;30(7):337-340. doi: 10.1097/MBC.0000000000000843. PMID: 31449137; PMCID: PMC7115924.
Ambika PL, Basu D, Nair SC, Kar R. Utility of International Society on Thrombosis and Hemostasis Bleeding Assessment Tool (ISTH-BAT) in Patients with Inherited Bleeding Disorders: A Cross-Sectional Study from Southern India. Indian J Hematol Blood Transfus. 2022 Jan;38(1):122-131. doi: 10.1007/s12288-021-01435-8. Epub 2021 Apr 15. PMID: 35125720; PMCID: PMC8804127.
Rastogi S, Chandran Nair S, Murugan P, Sukumar AS, Mammen JJ, Mullai S. Overall equipment effectiveness, efficiency and slide review analysis of high-end hematology analyzers. Pract Lab Med. 2022 Apr 18;30:e00275. doi: 10.1016/j.plabm.2022.e00275. PMID: 35601458; PMCID: PMC9117814.
Abbas S, Kini A, Srivastava VM, M MT, Nair SC, Abraham A, Mathews V, George B, Kumar S, Venkatraman A, Srivastava A. Coexistence of aberrant hematopoietic and stromal elements in myelodysplastic syndromes. Blood Cells Mol Dis. 2017 Jul;66:37-46. doi: 10.1016/j.bcmd.2017.08.004. Epub 2017 Aug 9. PMID: 28822917.
Jayaram A, Mathews NS, Nair SC, Geevar T, Rose W, Verghese VP, Mathuram AJ, Gunasekaran K, Abraham AM, Mammen JJ. High fluorescent lymphocyte cell count and scattergram patterns on the Sysmex XN series cell counters-Novel parameters in early and reliable diagnosis of dengue on a background of acute febrile illness. Int J Lab Hematol. 2021 Aug;43(4):O156-O160. doi: 10.1111/ijlh.13478. Epub 2021 Jan 25. PMID: 33491304.
Zachariah U, Nair SC, Goel A, Balasubramanian KA, Mackie I, Elias E, Eapen CE. Targeting raised von Willebrand factor levels and macrophage activation in severe COVID-19: Consider low volume plasma exchange and low dose steroid. Thromb Res. 2020 Aug;192:2. doi: 10.1016/j.thromres.2020.05.001. Epub 2020 May 5. PMID: 32403033; PMCID: PMC7198395.
Sen D, Gadkari RA, Sudha G, Gabriel N, Kumar YS, Selot R, Samuel R, Rajalingam S, Ramya V, Nair SC, Srinivasan N, Srivastava A, Jayandharan GR. Targeted modifications in adeno-associated virus serotype 8 capsid improves its hepatic gene transfer efficiency in vivo. Hum Gene Ther Methods. 2013 Apr;24(2):104-16. doi: 10.1089/hgtb.2012.195. PMID: 23442071; PMCID: PMC3732127. Link
Vijayalekshmi B, Sharma A, Prabhu SB, Nair SC, Mammen J, Goel A, Zachariah UG, Dutta AK, Balasubramanian KA, Elias E, Eapen CE. Reticuloendothelial activation correlates with disease severity and predicts mortality in severe alcoholic hepatitis. Eur J Gastroenterol Hepatol. 2021 Dec 1;33(1S Suppl 1):e329-e334. doi: 10.1097/MEG.0000000000002056. PMID: 33470708.
Rasalam JE, Kumar S, Sujith K, Fouzia NA, Palle A, Daniel D, Nair SC. Sickle cells are not necessarily protective against falciparum- A case report. Asian J Transfus Sci. 2022 Jul-Dec;16(2):266-268. doi: 10.4103/ajts.ajts_122_21. Epub 2022 May 26. PMID: 36687533; PMCID: PMC9855217. Link
Alexander V, Rasalam JE, Kumar S, Daniel D, Nair SC, Subramani K, Chacko B, James EJ, David VG, Varughese S, Patel L, Jayalakshmi VT, Singh KA, Kumar S, Zachariah U, Goel A, Eapen CE. Transfusion-related lung complications are uncommon in non-ventilated liver failure patients undergoing low-volume plasma exchange. Indian J Gastroenterol. 2023 Aug 12. doi: 10.1007/s12664-023-01429-6. Epub ahead of print. PMID: 37572266. Link
5 NOVEMBER 2021 | VOLUME 138, NUMBER Supplement 1
Santhosh E. Kumar, Ashish Goel, Uday Zachariah, Sukesh C. Nair, Vinoi G. David, Santosh Varughese, Prashanth B. Gandhi, Amit Barpha, Anand Sharma, Balakrishnan Vijayalekshmi, Kunissery A. Balasubramanian, Elwyn Elias, Chundamannil Eapen Eapen, Low Volume Plasma Exchange and Low Dose Steroid Improve Survival in Patients With Alcohol-Related Acute on Chronic Liver Failure and Severe Alcoholic Hepatitis – Preliminary Experience, Journal of Clinical and Experimental Hepatology, 2021, ISSN 0973-6883, https://doi.org/10.1016/j.jceh.2021.07.010. (https://www.sciencedirect.com/science/article/pii/S0973688321001778) Abstract: Background Alcohol-related acute on chronic liver failure (A-ACLF) patients have high short-term mortality and are poor candidates for steroid therapy. Plasma exchange (PLEX) improves survival in ACLF patients. We analyzed our experience with low volume PLEX (50% of plasma volume exchanged per session) and low dose steroids to treat A-ACLF patients. Methods We retrospectively compared the efficacy of low volume PLEX and low-dose steroids with standard medical treatment (SMT) in A-ACLF patients treated at our center between November 2017 to June 2019. The primary study outcome was one-year survival. Results Twenty-one A-ACLF patients in PLEX group [age 40 (29–56) years, median (range); MELD score 31 (29–46)] and 29 A-ACLF patients in SMT group [age 41.5 (28–63) years, MELD score 37 (21–48)] were studied. All 50 study patients had severe alcoholic hepatitis [mDF 84.7 (50–389)]. PLEX group patients had 3 (1–7) PLEX sessions with 1.5 (1.4–1.6) liters of plasma exchanged per session and oral Prednisolone 20 mg daily, tapered over 1 month. Kaplan Meier analysis showed better survival over 1 year in the PLEX group compared to the SMT group (P = 0.03). There was renal dysfunction in 10 patients in the PLEX group, which normalized in six patients after PLEX. Conclusion
Reddy S, Anoop S, Jebasingh FK, Dasgupta R, Joseph M, Saravanan B, Volena R, Mani T, Somasundaram S, Bhattacharji S, Nair SC, Paul RD, Thomas N. Differentials in dietary intake of macro and micronutrients in patients with type 2 diabetes and foot ulcers: Observations from a pilot study. Clin Nutr ESPEN. 2022 Feb;47:170-176. doi: 10.1016/j.clnesp.2021.12.023. Epub 2021 Dec 22. PMID: 35063197. Link
David S, Kamath V, Kulkarni U, Vijayan R, Korula A, Fouzia NA, Nisham PN, Srivastava A, Lakshmi KM, Balasubramanian P, George B ,Nair SC. Coagulopathy in Acute Promyelocytic Leukemia: Strategies to Improve Assessment of Hemostatic Risk . Blood (2015) 126 (23): 3758.
Dave RG, Geevar T, Aaron S, Ninan Benjamin R, Mammen J, Kumar S, Vijayan R, Gowri M, C Nair S. Diagnostic utility of flow cytometry based coated-platelets assay as a biomarker to predict thrombotic or hemorrhagic phenotype in acute stroke. Cytometry B Clin Cytom. 2021 Jun 21. doi: 10.1002/cyto.b.22026. Epub ahead of print. PMID: 34152689.
Kumar SE, Goel A, Zachariah U, Nair SC, David VG, Varughese S, Gandhi PB, Barpha A, Sharma A, Vijayalekshmi B, Balasubramanian KA, Elias E, Eapen CE. Low Volume Plasma Exchange and Low Dose Steroid Improve Survival in Patients With Alcohol-Related Acute on Chronic Liver Failure and Severe Alcoholic Hepatitis - Preliminary Experience. J Clin Exp Hepatol. 2022 Mar-Apr;12(2):372-378. doi: 10.1016/j.jceh.2021.07.010. Epub 2021 Jul 21. PMID: 35535077; PMCID: PMC9077153.
Kulkarni UP, Selvarajan S, Lionel S, Prakash MA, Palani HK, Balasundaram N, Venkataraman A, Korula A, Devasia AJ, Fouzia NA, Janet NB, Nair SC, Abraham A, Mani T, Lakshmanan J, Arunachalam AK, Balasubramanian P, George B, Mathews V. Real world data with concurrent retinoic acid and arsenic trioxide for the treatment of acute promyelocytic leukemia. Blood Cancer J. 2022 Jan 31;12(1):22. doi: 10.1038/s41408-022-00619-3. PMID: 35102152; PMCID: PMC8803919.
Shima M, Thachil J, Nair SC, Srivastava A; Scientific and Standardization Committee. Towards standardization of clot waveform analysis and recommendations for its clinical applications. J Thromb Haemost. 2013 Jul;11(7):1417-20. doi: 10.1111/jth.12287. PMID: 23648068.
Shima M, Thachil J, Nair SC, Srivastava A; Scientific and Standardization Committee. Towards standardization of clot waveform analysis and recommendations for its clinical applications. J Thromb Haemost. 2013 Jul;11(7):1417-20. doi: 10.1111/jth.12287. PMID: 23648068.
Siromani U, Tsubaki T, Daniel D, Mammen JJ, Nair SC. Perspectives and attitudes to voluntary blood donation in a tertiary referral hospital blood bank. Asian J Transfus Sci. 2013 Jul;7(2):158-9. doi: 10.4103/0973-6247.115589. PMID: 24014951; PMCID: PMC3757781.
Siromani U, Rita Isaac TT, Daniel D, Kg S, Mammen JJ, Nair SC. Recruitment and retention of voluntary blood donors through electronic communication. Acta Inform Med. 2013;21(2):142. doi: 10.5455/aim.2013.21.142-142. PMID: 24324291; PMCID: PMC3766533. Link
Ganapati A, Mathew J, Yadav B, Kabeerdoss J, Gowri M, Dave RG, Thankachen R, Nair SC. Comparison of Point-of-Care PT-INR by Hand-Held Device with Conventional PT-INR Testing in Anti-phospholipid Antibody Syndrome Patients on Oral Anticoagulation. Indian J Hematol Blood Transfus. 2023 Jul;39(3):450-455. doi: 10.1007/s12288-022-01611-4. Epub 2022 Nov 21. PMID: 37304492; PMCID: PMC10247631.
Aaron R, Premkumar K, Chapla A, Vijayalekshmi B, Zachariah U, Elias E, Kodiatte TA, Daniel D, Jude J, Balasubramanian KA, Nair SC, Thomas N, Ramakrishna B, Eapen CE, Goel A. Focused panel sequencing points to genetic predisposition in non-cirrhotic intrahepatic portal hypertension patients in India. Indian J Gastroenterol. 2023 Oct 5. doi: 10.1007/s12664-023-01454-5. Epub ahead of print. PMID: 37796423.
Siromani U, Thasian T, Selvaraj KG, Daniel D, Mammen JJ, Nair SC, Isaac R. Determinants which influence to donate blood voluntarily at a northeast district of the state of Tamil Nadu, South India. Indian J Community Med. 2014 Oct;39(4):250. doi: 10.4103/0970-0218.143031. PMID: 25364151; PMCID: PMC4215508.
Sardar D, Mathews N, Mammen J, Nair SC, Jacob S, Patel L, Thomas A, Jhanwar S, Sharma A, Sen M, Vijayalekshmi B, Balasubramanian KA, Subramani K, Thomas L, Abhilash KPP, Zachariah U, Elias E, Goel A, Eapen CE. Rodenticidal hepatotoxicity: Raised plasma Von Willebrand factor levels predict in-hospital survival and preliminary report of the outcome of Von Willebrand factor reducing management protocol. Indian J Gastroenterol. 2019 Dec;38(6):527-533. doi: 10.1007/s12664-019-00989-w. Epub 2020 Feb 19. PMID: 32077040.
Kulkarni UP, Selvarajan S, Fouzia NA, Lionel S, Nair SC, Balasubramanian P, Mani T, Abraham A, George B, Mathews V. Intracranial bleeding in acute promyelocytic leukemia treated with arsenic trioxide based regimens is associated with induction mortality but not with relapse. Blood Cancer J. 2023 Jun 22;13(1):94. doi: 10.1038/s41408-023-00873-z. PMID: 37349334; PMCID: PMC10287743.
Kitchen S, Adcock DM, Dauer R, Kristoffersen AH, Lippi G, Mackie I, Marlar RA, Nair S. International Council for Standardisation in Haematology (ICSH) recommendations for collection of blood samples for coagulation testing. Int J Lab Hematol. 2021 Aug;43(4):571-580. doi: 10.1111/ijlh.13584. Epub 2021 Jun 7. PMID: 34097805.
Srivastava VM, Nair SC, Sappani M, Manipadam MT, Kulkarni UP, Devasia AJ, Fouzia NA, Korula A, Lakshmi KM, Abraham A, Srivastava A. Cytogenetic profile of 1791 adult acute myeloid leukemia in India. Mol Cytogenet. 2023 Sep 16;16(1):24. doi: 10.1186/s13039-023-00653-1. PMID: 37716945; PMCID: PMC10504794.
Parameswaran A, Krishnamoorthy VP, Oommen AT, Jasper A, Korula RJ, Nair SC, Poonnoose PM. Is pre-operative assessment of coagulation profile with Thrombelastography (TEG) useful in predicting venous thromboembolism (VTE) following orthopaedic surgery? J Clin Orthop Trauma. 2016 Oct-Dec;7(Suppl 2):225-229. doi: 10.1016/j.jcot.2016.08.003. Epub 2016 Aug 24. PMID: 28053389; PMCID: PMC5197038.
Siromani U, Rajaiah M, Daniel D, Mammen JJ, Nair SC. Ahead to 100% of voluntary nonremunerated blood donation at a tertiary referral hospital blood bank in South India. Asian J Transfus Sci. 2012 Jul;6(2):190. doi: 10.4103/0973-6247.98954. PMID: 22988391; PMCID: PMC3439765.
Joseph AJ, Simon EG, Chandran S, Chacko A. Pancreatic juice crystals: is it an early marker of chronic pancreatitis? Gastrointest Endosc. 2009 Mar;69(3 Pt 1):593-5. doi: 10.1016/j.gie.2008.05.012. Epub 2008 Aug 8. PMID: 18691711. Link
S B MJ, Chacko B, Selvarajan S, Peter JV, Geevar T, Dave RG, Georgy JT, Zachariah A, George T, Sathyendra S, Hansdak SG, Krishnaswami RK, Thangakunam B, Gupta R, Karuppusami R, Nair SC, Srivastava A. Biomarkers of coagulation, endothelial, platelet function, and fibrinolysis in patients with COVID-19: a prospective study. Sci Rep. 2024 Jan 23;14(1):2011. doi: 10.1038/s41598-024-51908-9. PMID: 38263377; PMCID: PMC10805716.
Palani HK, Ganesan S, Balasundaram N, Venkatraman A, Kulkarni U, Korula A, Nair SC, Mani T, Balasubramanian P, Abraham A, Puttamallesh VN, Gowda H, Mathews V. Cystatin F a potential diagnostic biomarker in acute promyelocytic leukemia. Ann Hematol. 2024 Mar 1. doi: 10.1007/s00277-024-05673-4. Epub ahead of print. PMID: 38427058.
Perla HT, Thomson VS, Attumalil TV, Geevar T, Alex AG, Dave RG, Nair SC, Gowri SM, Mony PK, George P, Joseph G. Randomized, Double-Blind, Active Comparator Pharmacodynamic Study of Platelet Inhibition with Crushed and Integral Formulations of Clopidogrel and Ticagrelor in Acute Coronary Syndrome. Am J Cardiovasc Drugs. 2023 Jul;23(4):455-466. doi: 10.1007/s40256-023-00591-8. Epub 2023 Jun 23. PMID: 37351814.
Mariappan R, Kumar S, Raju K, Daniel D, Nair SC, Subramani S. Comparing two techniques of performing an epidural catheter-assisted epidural blood patch using a 20 ml syringe versus a 5 ml syringe and its effect on clotting time, the strength of clot retraction and haemolysis - A prospective in vitro study (EC-EBP study). Indian J Anaesth. 2023 Jun;67(6):544-547. doi: 10.4103/ija.ija_849_22. Epub 2023 Jun 14. PMID: 37476432; PMCID: PMC10355359.
Balandina AN, Koltsova EM, Shibeko AM, Kuprash AD, Budkova VA, Demina IA, Ignatova AA, Fadeeva OA, Vijay R, Nair SC, Srivastava A, Shi Q, Ataullakhanov FI, Panteleev MA. Platelets provide robustness of spatial blood coagulation to the variation of initial conditions. Thromb Res. 2023 Oct;230:133-143. doi: 10.1016/j.thromres.2023.09.003. Epub 2023 Sep 13. PMID: 37717370.
Moffat KA, Kiencke V, Blanco AN, McLintock C, Peyvandi F, de Maat MPM, Adams MJ, Angchaisuksiri P, Nair S, Tsuda H, Haddad M, Renné T, Clark RC, Ross MT. International Society on Thrombosis and Haemostasis core curriculum project: Core competencies in laboratory thrombosis and hemostasis. J Thromb Haemost. 2019 Nov;17(11):1848-1859. doi: 10.1111/jth.14601. Epub 2019 Sep 5. PMID: 31400072.