Professor
Christian Medical College Vellore, Ida Scudder Road, Vellore – 632004, Tamil Nadu, India
Mohapatra A, Kakde S, Annapandian VM, Valson AT, Duhli N, Korula A, Matthai SM, Pulimood AB, David VG, Alexander S, Jacob S, Varughese S, Basu G, Tamilarasi V, John GT. Spectrum of biopsy proven renal disease in South Asian children: Two decades at a tropical tertiary care centre. Nephrology (Carlton). 2018 Nov;23(11):1013-1022. doi: 10.1111/nep.13160. PMID: 28846194.
Matthai SM, Jacob S, Bindra MS, David VG, Varughese S. Nephropathic cystinosis presenting with uveitis: Report of a "Can't See, Can't Pee" situation. Indian J Pathol Microbiol. 2019 Jul-Sep;62(3):457-460. doi: 10.4103/IJPM.IJPM_623_18. PMID: 31361240.
Agrawal V, Valson AT, Mohapatra A, David VG, Alexander S, Jacob S, Bakthavatchalam YD, Prakash JAJ, Balaji V, Varughese S. Fast and furious: a retrospective study of catheter-associated bloodstream infections with internal jugular nontunneled hemodialysis catheters at a tropical center. Clin Kidney J. 2019 Feb 5;12(5):737-744. doi: 10.1093/ckj/sfy138. PMID: 31583098; PMCID: PMC6768464.
David VG, Korula A, Choudhrie L, Michael JS, Jacob S, Jacob CK, John GT. Cryptococcal granulomatous interstitial nephritis and dissemination in a patient with untreated lupus nephritis. Nephrol Dial Transplant. 2009 Oct;24(10):3243-5. doi: 10.1093/ndt/gfp293. Epub 2009 Jun 13. PMID: 19525518.
Jayanth ST, Dangi AD, Mukha RP, Kumar S, Varughese S, David VG, Valson A, Chandrasingh J, Devasia A, Kekre N. Renal transplantation into optimized abnormal lower urinary tract - Impact on graft outcomes, patient survival, and complications. Indian J Urol. 2019 Jan-Mar;35(1):67-72. doi: 10.4103/iju.IJU_203_18. PMID: 30692727; PMCID: PMC6334589.
Valson AT, David VG, Balaji V, John GT. Multifocal bacterial osteomyelitis in a renal allograft recipient following urosepsis. Indian J Nephrol. 2014 May;24(3):189-92. doi: 10.4103/0971-4065.132022. PMID: 25120300; PMCID: PMC4127842.
Mohapatra A, Kakde S, Annapandian VM, Valson AT, Duhli N, Korula A, Matthai SM, Pulimood AB, David VG, Alexander S, Jacob S, Varughese S, Basu G, Tamilarasi V, John GT. Spectrum of biopsy proven renal disease in South Asian children: Two decades at a tropical tertiary care centre. Nephrology (Carlton). 2018 Nov;23(11):1013-1022. doi: 10.1111/nep.13160. PMID: 28846194.
Matthai SM, Jacob S, Bindra MS, David VG, Varughese S. Nephropathic cystinosis presenting with uveitis: Report of a "Can't See, Can't Pee" situation. Indian J Pathol Microbiol. 2019 Jul-Sep;62(3):457-460. doi: 10.4103/IJPM.IJPM_623_18. PMID: 31361240.
Agrawal V, Valson AT, Mohapatra A, David VG, Alexander S, Jacob S, Bakthavatchalam YD, Prakash JAJ, Balaji V, Varughese S. Fast and furious: a retrospective study of catheter-associated bloodstream infections with internal jugular nontunneled hemodialysis catheters at a tropical center. Clin Kidney J. 2019 Feb 5;12(5):737-744. doi: 10.1093/ckj/sfy138. PMID: 31583098; PMCID: PMC6768464.
David VG, Korula A, Choudhrie L, Michael JS, Jacob S, Jacob CK, John GT. Cryptococcal granulomatous interstitial nephritis and dissemination in a patient with untreated lupus nephritis. Nephrol Dial Transplant. 2009 Oct;24(10):3243-5. doi: 10.1093/ndt/gfp293. Epub 2009 Jun 13. PMID: 19525518.
Jayanth ST, Dangi AD, Mukha RP, Kumar S, Varughese S, David VG, Valson A, Chandrasingh J, Devasia A, Kekre N. Renal transplantation into optimized abnormal lower urinary tract - Impact on graft outcomes, patient survival, and complications. Indian J Urol. 2019 Jan-Mar;35(1):67-72. doi: 10.4103/iju.IJU_203_18. PMID: 30692727; PMCID: PMC6334589.
Valson AT, David VG, Balaji V, John GT. Multifocal bacterial osteomyelitis in a renal allograft recipient following urosepsis. Indian J Nephrol. 2014 May;24(3):189-92. doi: 10.4103/0971-4065.132022. PMID: 25120300; PMCID: PMC4127842.
Ponnuvel S, Fletcher GJ, Anantharam R, Varughese S, David VG, Abraham P. Clinical utility of hepatitis C virus core antigen (HCVcAg) assay to identify active HCV infection in hemodialysis and renal transplant patients. PLoS One. 2021 Apr 22;16(4):e0250263. doi: 10.1371/journal.pone.0250263. PMID: 33886631; PMCID: PMC8061997.
Radhakrishnan RC, Varughese S, Chandran A, Jacob S, David VG, Alexander S, Mohapatra A, Valson AT, Gopal B, Palani C, Jose A, Antonisamy B, Tamilarasi V. Effects of Individualized Dialysate Sodium Prescription in Hemodialysis - Results from a Prospective Interventional Trial. Indian J Nephrol. 2020 Jan-Feb;30(1):3-7. doi: 10.4103/ijn.IJN_391_18. Epub 2019 Dec 27. PMID: 32015592; PMCID: PMC6977377.
Radhakrishnan RC, Gopal B, Zachariah UG, Abraham P, Mohapatra A, Valson AT, Alexander S, Jacob S, Tulsidas KS, David VG, Varughese S. The long-term impact of hepatitis C infection in kidney transplantation in the pre-direct acting antiviral era. Saudi J Kidney Dis Transpl. 2018 Sep-Oct;29(5):1092-1099. doi: 10.4103/1319-2442.243964. PMID: 30381505 PMCID: PMC7170713. Link
Jayanth ST, Dangi AD, Mukha RP, Kumar S, Varughese S, David VG, Valson A, Chandrasingh J, Devasia A, Kekre N. Renal transplantation into optimized abnormal lower urinary tract - Impact on graft outcomes, patient survival, and complications. Indian J Urol. 2019 Jan-Mar;35(1):67-72. doi: 10.4103/iju.IJU_203_18. PMID: 30692727; PMCID: PMC6334589.
M. SELVIN SUNDAR RAJ, M. Lalwani, R. Alam, A. T.Valson, T. Athul, J. Joseph Eapen, E. Elias John, S. Yusuf, A. Vc, M. Joy, S. Alexander, S. Varughese, V. George David, POS-769 DOES EARLY ASYMPTOMATIC BACTERIURIA AFFECT GRAFT OUTCOMES IN KIDNEY TRANSPLANT RECIPIENTS FROM SOUTH ASIA?, Kidney International Reports, Volume 6, Issue 4, Supplement, 2021, Pages S335-S336, ISSN 2468-0249, https://doi.org/10.1016/j.ekir.2021.03.801. (https://www.sciencedirect.com/science/article/pii/S2468024921009475)
R. ALAM, S. Sundar Raj, M. Lalwani, J. Joseph Eapen, A. Thomas, E. Elias John, S. Yusuf, A. Vc, S. Alexander, V. George David, S. Varughese, A. T.Valson, POS-687 DONOR CYSTATIN C eGFR> 100 ml/min/1.73m2 IS AN INDEPENDENT PREDICTOR OF GRAFT SURVIVAL IN INDIAN KIDNEY TRANSPLANT RECIPIENTS, Kidney International Reports, Volume 6, Issue 4, Supplement, 2021,Page S300, ISSN 2468-0249, https://doi.org/10.1016/j.ekir.2021.03.719. (https://www.sciencedirect.com/science/article/pii/S2468024921008652)
Asad RA, Valson AT, Kavitha V, Korula A, Eapen A, Rebekah G, Jacob S, Pathak H, Alexander S, Mohapatra A, David VG, Varughese S, Tamilarasi V, Basu G. Safety and utility of kidney biopsy in patients with estimated glomerular filtration rate < 30 ml/min/1.73 m2. Nephrology (Carlton). 2021 Aug;26(8):659-668. doi: 10.1111/nep.13879. Epub 2021 Apr 14. PMID: 33779021. Link
Agrawal V, Valson AT, Bakthavatchalam YD, Kakde S, Mohapatra A, David VG, Alexander S, Jacob S, Jude Prakash JA, Veeraraghavan B, Varughese S. Skin Colonizers and Catheter Associated Blood Stream Infections in Incident Indian Dialysis Patients. Indian J Nephrol. 2022 Jan-Feb;32(1):34-41. doi: 10.4103/ijn.IJN_400_20. Epub 2021 Apr 8. PMID: 35283564; PMCID: PMC8916144.
Mammen S, Koshy GC, Khurana A, David V. Endovascular repair of iatrogenic subclavian artery pseudo-aneurysm. Saudi J Kidney Dis Transpl. 2015 Sep;26(5):1023-5. doi: 10.4103/1319-2442.164598. PMID: 26354585.
Behera MR, John EE, Thomas A, David VG, Alexander S, Mohapatra A, Valson AT, Jacob S, Kakde S, Koshy PM, Rajan G, Varughese S. Difficult cannulation of hemodialysis arteriovenous fistula - Role of imaging in access management (DICAF STUDY). J Vasc Access. 2021 May 12:11297298211015097. doi: 10.1177/11297298211015097. Epub ahead of print. PMID: 33977819.
John EE, Thomas A, Eapen JJ, Yusuf S, Roy S, Valson AT, David VG, Varughese S, Alexander S. Latency, Anti-Bacterial Resistance Pattern, and Bacterial Infection-Related Glomerulonephritis. Clin J Am Soc Nephrol. 2021 Aug;16(8):1210-1220. doi: 10.2215/CJN.18631120. Epub 2021 Jun 7. PMID: 34099500; PMCID: PMC8455032
Mathew BS, Mathew SK, Aruldhas BW, Prabha R, Gangadharan N, David VG, Varughese S, John GT. Analytical and clinical validation of dried blood spot and volumetric absorptive microsampling for measurement of tacrolimus and creatinine after renal transplantation. Clin Biochem. 2022 Jul-Aug;105-106:25-34. doi: 10.1016/j.clinbiochem.2022.04.014. Epub 2022 Apr 28. PMID: 35490728. Link
Valson AT, George RR, Lalwani M, Balusamy D, Albert DS, Abraham A, Richie B, Samuel NP, Eapen JJ, Thomas A, John EE, Yusuf S, Chidambaram AV, Alexander S, David VG, Varughese S, Jesudoss I, Ravindran V. Impact of the lockdown on patients receiving maintenance hemodialysis at a tertiary care facility in Southern India – A mixed-methods approach. Indian J Nephrol 2022;32:(3)256-61. DOI: 10.4103/ijn.IJN_561_20
Behera MR, John EE, Thomas A, David VG, Alexander S, Mohapatra A, Valson AT, Jacob S, Kakde S, Koshy PM, Rajan G, Varughese S. Difficult cannulation of hemodialysis arteriovenous fistula - Role of imaging in access management (DICAF STUDY). J Vasc Access. 2022 Nov;23(6):877-884. doi: 10.1177/11297298211015097. Epub 2021 May 12. PMID: 33977819.
Varughese S, Alexander S, Valson AT, Mohapatra A, David VG, Jacob S, John EE, Koshy PM, Eapen JJ, Thomas A, Yusuf S. Blind Bedside Peritoneal Dialysis Catheter Repositioning: An Innovative Technique. Indian J Nephrol. 2021 May-Jun;31(3):311-313. doi: 10.4103/ijn.IJN_417_19. Epub 2021 Apr 6. PMID: 34376952; PMCID: PMC8330660. Link
Chanda R, Singh S, Eapen A, David VG, Mukha RP, Pandian RM, Antonisamy B, Deborah MN, Eapen JJ, Thomas A, John EE, Yusuf S, Alexander S, Varughese S, Valson AT. Whole and cortical kidney volume predict 5-year post-nephrectomy eGFR in Indian living kidney donors. Nephrology (Carlton). 2023 Feb;28(2):136-147. doi: 10.1111/nep.14129. Epub 2022 Nov 25. PMID: 36342651.
Alexander S, Varughese S, Franklin R, Roy S, Rebekah G, David VG, Mohapatra A, Valson AT, Jacob S, Koshy PM, Rajan G, Daha MR, Feehally J, Barratt J, John GT. Epidemiology, baseline characteristics and risk of progression in the first South-Asian prospective longitudinal observational IgA nephropathy cohort. Kidney Int Rep. 2020 Dec 7;6(2):414-428. doi: 10.1016/j.ekir.2020.11.026. PMID: 33615067; PMCID: PMC7879115.
Alexander V, Rasalam JE, Kumar S, Daniel D, Nair SC, Subramani K, Chacko B, James EJ, David VG, Varughese S, Patel L, Jayalakshmi VT, Singh KA, Kumar S, Zachariah U, Goel A, Eapen CE. Transfusion-related lung complications are uncommon in non-ventilated liver failure patients undergoing low-volume plasma exchange. Indian J Gastroenterol. 2023 Aug 12. doi: 10.1007/s12664-023-01429-6. Epub ahead of print. PMID: 37572266. Link
Santhosh E. Kumar, Ashish Goel, Uday Zachariah, Sukesh C. Nair, Vinoi G. David, Santosh Varughese, Prashanth B. Gandhi, Amit Barpha, Anand Sharma, Balakrishnan Vijayalekshmi, Kunissery A. Balasubramanian, Elwyn Elias, Chundamannil Eapen Eapen, Low Volume Plasma Exchange and Low Dose Steroid Improve Survival in Patients With Alcohol-Related Acute on Chronic Liver Failure and Severe Alcoholic Hepatitis – Preliminary Experience, Journal of Clinical and Experimental Hepatology, 2021, ISSN 0973-6883, https://doi.org/10.1016/j.jceh.2021.07.010. (https://www.sciencedirect.com/science/article/pii/S0973688321001778) Abstract: Background Alcohol-related acute on chronic liver failure (A-ACLF) patients have high short-term mortality and are poor candidates for steroid therapy. Plasma exchange (PLEX) improves survival in ACLF patients. We analyzed our experience with low volume PLEX (50% of plasma volume exchanged per session) and low dose steroids to treat A-ACLF patients. Methods We retrospectively compared the efficacy of low volume PLEX and low-dose steroids with standard medical treatment (SMT) in A-ACLF patients treated at our center between November 2017 to June 2019. The primary study outcome was one-year survival. Results Twenty-one A-ACLF patients in PLEX group [age 40 (29–56) years, median (range); MELD score 31 (29–46)] and 29 A-ACLF patients in SMT group [age 41.5 (28–63) years, MELD score 37 (21–48)] were studied. All 50 study patients had severe alcoholic hepatitis [mDF 84.7 (50–389)]. PLEX group patients had 3 (1–7) PLEX sessions with 1.5 (1.4–1.6) liters of plasma exchanged per session and oral Prednisolone 20 mg daily, tapered over 1 month. Kaplan Meier analysis showed better survival over 1 year in the PLEX group compared to the SMT group (P = 0.03). There was renal dysfunction in 10 patients in the PLEX group, which normalized in six patients after PLEX. Conclusion
J. JOHNY, S. Roy, E.E. John, S. Yusuf, V.G. David, A. T Valson, A. Thomas, J. J Eapen, S. Varughese, S. Alexander, POS-150 CLINICAL AND HISTOPATHOLOGICAL PROFILE AND OUTCOME OF PATIENTS WITH BIOPSY PROVEN PGNMID (PROLIFERATIVE GLOMERULONEPHRITIS WITH MONOCLONAL IMMUNOGLOBULIN DEPOSITS), Kidney International Reports, Volume 6, Issue 4, Supplement, 2021, Page S60, ISSN 2468-0249, https://doi.org/10.1016/j.ekir.2021.03.160. (https://www.sciencedirect.com/science/article/pii/S2468024921003065)
Parthasarathy R, David VG, Rohit A, Mathew M, Sabu S, Babu M, Abraham G. COVID-19 Infection in CAPD Patients: A Single-Center Indian Experience. Indian J Nephrol. 2022 Mar-Apr;32(2):186-188. doi: 10.4103/ijn.IJN_522_20. Epub 2022 Jan 5. PMID: 35603112; PMCID: PMC9121717.
Thomas L, Chandran J, Goel A, Jacob E, Chacko B, Subramani K, Agarwal I, Varughese S, David VG, Daniel D, Mammen J, Balakrishnan V, Balasubramanian KA, Lionel AP, Adhikari DD, Abhilash KPP, Elias E, Eapen CE, Zachariah U. Improving Transplant-free Survival With Low-volume Plasma Exchange to Treat Children With Rodenticide Induced Hepatotoxicity. J Clin Exp Hepatol. 2023 Mar-Apr;13(2):252-258. doi: 10.1016/j.jceh.2022.10.013. Epub 2022 Nov 12. PMID: 36950489; PMCID: PMC10025587.
Matthai SM, Jacob S, Devasia AJ, Bindra M, David VG, Varughese S. Unmasking and successful management of light chain deposition disease of kidney in pregnancy: a complex case, mirroring the complex needs of pregnancy with kidney disease in India. J Nephrol. 2018 Oct;31(5):785-791. doi: 10.1007/s40620-018-0532-0. Epub 2018 Sep 5. PMID: 30187379.
Mohapatra A, Valson AT, Annapandian VM, David VG, Alexander S, Jacob S, Kakde S, Kumar S, Devasia A, Vijayakumar TS, Tamilarasi V, Jacob CK, Basu G, John GT, Varughese S. Post-transplant complications, patient, and graft survival in pediatric and adolescent kidney transplant recipients at a tropical tertiary care center across two immunosuppression eras. Pediatr Transplant. 2021 Sep;25(6):e13973. doi: 10.1111/petr.13973. Epub 2021 Jan 19. PMID: 33463876.
Asad RA, Valson AT, Kavitha V, Korula A, Eapen A, Rebekah G, Jacob S, Pathak H, Alexander S, Mohapatra A, David VG, Varughese S, Tamilarasi V, Basu G. Safety and utility of kidney biopsy in patients with estimated glomerular filtration rate < 30 ml/min/1.73 m2. Nephrology (Carlton). 2021 Aug;26(8):659-668. doi: 10.1111/nep.13879. Epub 2021 Apr 14. PMID: 33779021.
Valson AT, Sundaram M, David VG, Deborah MN, Varughese S, Basu G, Mohapatra A, Alexander S, Jose J, Roshan J, Simon B, Rebekah G, Tamilarasi V, Jacob CK. Profile of incident chronic kidney disease related-mineral bone disorders in chronic kidney disease Stage 4 and 5: A hospital based cross-sectional survey. Indian J Nephrol. 2014 Mar;24(2):97-107. doi: 10.4103/0971-4065.127897. PMID: 24701042; PMCID: PMC3968617.
Singh KA, Kumar SE, Zachariah UG, Daniel D, David V, Subramani K, Pichamuthu K, Jacob E, Kodiatte TA, Eapen CE, Goel A. Single-Centre Experience With Low-Volume Plasma Exchange and Low-Dose Steroid to Treat Patients With Idiosyncratic Drug-Induced Acute Liver Failure. J Clin Exp Hepatol. 2024 Mar-Apr;14(2):101303. doi: 10.1016/j.jceh.2023.11.003. Epub 2023 Nov 7. PMID: 38076447; PMCID: PMC10698001.
Varughese S, Sundaram M, Basu G, David VG, Mohapatra A, Alexander S, Tamilarasi V. Percutaneous PD catheter insertion after past abdominal surgeries. Indian J Nephrol. 2012 May;22(3):230-1. doi: 10.4103/0971-4065.98785. PMID: 23087566; PMCID: PMC3459535.
John EE, Roy S, Devasia AJ, Karuppusami R, Jose N, Mani SSR, Eapen JJ, Yusuf S, Thomas A, Valson AT, David VG, Mathews V, Biju George, Varughese S, Alexander S. Patterns of Renal Dysfunction and Profile of Kidney Biopsies in Hematopoietic Stem Cell Transplant Recipients. Glomerular Dis. 2023 Mar 14;3(1):98-115. doi: 10.1159/000529699. PMID: 37064012; PMCID: PMC10098275.
John EE, Roy S, Eapen JJ, Karuppusami R, Jose N, Mani SSR, Johny J, Alam R, Yusuf S, Thomas A, Valson AT, David VG, Varughese S, Alexander S. Bacterial infection-related glomerulonephritis in patients with diabetes. Nephrology (Carlton). 2023 Nov;28(11):597-610. doi: 10.1111/nep.14222. Epub 2023 Jul 26. PMID: 37492933.
